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Author SHA1 Message Date
will king 5b271a41c5 Merge branch 'lognorm_sigma_prior' 1 year ago
will king f17f88728f Merge branch 'exploring_fixed_effects' 1 year ago
Will King cd90d8e28b reran analysis to get up to date stuff 1 year ago
Will King 7074fa6c32 Updated graphing code 1 year ago
Will King 6fcc8cda22 Fixed column issue in enrollment delay 1 year ago
Will King be77d1d38a Fixed error in column order that invalidated results
The columns for competitor drugs were placed in the wrong spot.
1 year ago
Will King c1ebd42639 Began exploring fixed effects' interpretation 1 year ago
will king 73407ac215 Merge branch 'main' of https://git.youainti.com/youainti/ClinicalTrialsEstimation 1 year ago
will king c29d696e5e recording home-pc version of recruitment status 1 year ago
Will 2f71e63e22 Removed results (images) from prior analyses.
There are a lot of images that have been collected from prior analyses.
I'm cleaning that up and changing the directory tree where they are
stored.
1 year ago
Will King 87d2077f6e Got new images for analysis
Based on updated data.
1 year ago
Will King 5a7e6ff299 Merge branch 'main' of https://git.youainti.com/youainti/ClinicalTrialsEstimation 1 year ago
Will King 26b3ce9b17 Updated analysis graphs and interpretation.
Also renamed some images to match what they represent.
The new .png files are from that. The renamed ones are from running the
analysis earlier.
1 year ago
will king c255652744 Merge branch 'main' of ssh://git.youainti.com:3022/youainti/ClinicalTrialsEstimation 2 years ago
will king 9656a59a19 removed unused Julia models 2 years ago
Will King d25f5c2a0e Ran an analysis for pharma and included all the output. 2 years ago

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Version: 1.0
RestoreWorkspace: Default
SaveWorkspace: Default
AlwaysSaveHistory: Default
EnableCodeIndexing: Yes
UseSpacesForTab: Yes
NumSpacesForTab: 2
Encoding: UTF-8
RnwWeave: Sweave
LaTeX: pdfLaTeX

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using Turing, StatsFuns
using Distributions, StatsPlots
using FillArrays
begin #creating synthetic data
βs = [1 2 3]'
x = Matrix([1:10 1:2:20 1:3:30])
X = (x .- mean(x,dims=1)) ./ std(x,dims=1)
t = [x for x=1:0.5:5.5]
s = rand([1,2],10)
σ= [2 3]
rand_draw1 = randn(10)
y = x*βs .+ σ[s]
end
@model function JointDurationStateModel(
DeviationFromExpectedDuration,
ConclusionStatus,
SnapshotState,
CurrentDuration,
)
# get dimensions
n,k = size(SnapshotState)
#hyperpriors priors
#Heirarchal parameters
#β ~ MvNormal(Fill(0,k),2)
η ~ MvNormal(Fill(0,k),2)
#Direct Priors
#σ_DFED ~ filldist(Exponential(1),2) #TODO: check implication of this form
#model
#μ = SnapshotState * β
p = StatsFuns.logistic.(SnapshotState * η)
#estimate ConclusionStatus model
ConclusionStatus .~ Bernoulli(p)
#Estimate DFED model
#=
for i in eachindex(ConclusionStatus)
DeviationFromExpectedDuration ~ Normal(
μ[ConclusionStatus[i]],
σ_DFED[ConclusionStatus[i]]
)
end
=#
end
model = JointDurationStateModel(y,s,X,t)
prior = JointDurationStateModel(fill(missing,size(y)),fill(missing,size(s)),X,t)
chain = sample(model,NUTS(0.85),2000)
plot(chain)

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---
title: "The Effects of market conditions on recruitment and completion of clinical trials"
author: "Will King"
format: html
editor: source
---
# Setup
```{r}
library(bayesplot)
available_mcmc(pattern = "_nuts_")
library(ggplot2)
library(patchwork)
library(tidyverse)
library(rstan)
library(tidyr)
library(ghibli)
#Resources: https://github.com/stan-dev/rstan/wiki/RStan-Getting-Started
#save unchanged models instead of recompiling
rstan_options(auto_write = TRUE)
#allow for multithreaded sampling
options(mc.cores = parallel::detectCores())
#test installation, shouldn't get any errors
#example(stan_model, package = "rstan", run.dontrun = TRUE)
```
```{r}
################ Pull data from database ######################
library(RPostgreSQL)
driver <- dbDriver("PostgreSQL")
get_data <- function(driver) {
con <- dbConnect(
driver,
user='root',
password='root',
dbname='aact_db',
host='will-office'
)
on.exit(dbDisconnect(con))
query <- dbSendQuery(
con,
# "select * from formatted_data_with_planned_enrollment;"
"
select
fdqpe.nct_id
--,fdqpe.start_date
--,fdqpe.current_enrollment
--,fdqpe.enrollment_category
,fdqpe.current_status
,fdqpe.earliest_date_observed
,fdqpe.elapsed_duration
,fdqpe.n_brands as identical_brands
,ntbtu.brand_name_count
,fdqpe.category_id
,fdqpe.final_status
,fdqpe.h_sdi_val
--,fdqpe.h_sdi_u95
--,fdqpe.h_sdi_l95
,fdqpe.hm_sdi_val
--,fdqpe.hm_sdi_u95
--,fdqpe.hm_sdi_l95
,fdqpe.m_sdi_val
--,fdqpe.m_sdi_u95
--,fdqpe.m_sdi_l95
,fdqpe.lm_sdi_val
--,fdqpe.lm_sdi_u95
--,fdqpe.lm_sdi_l95
,fdqpe.l_sdi_val
--,fdqpe.l_sdi_u95
--,fdqpe.l_sdi_l95
from formatted_data_with_planned_enrollment fdqpe
join \"Formularies\".nct_to_brands_through_uspdc ntbtu
on fdqpe.nct_id = ntbtu.nct_id
order by fdqpe.nct_id, fdqpe.earliest_date_observed
;
"
)
df <- fetch(query, n = -1)
df <- na.omit(df)
query2 <-dbSendQuery(con,"select count(*) from \"DiseaseBurden\".icd10_categories ic where \"level\"=1;")
n_categories <- fetch(query2, n = -1)
return(list(data=df,ncat=n_categories))
}
d <- get_data(driver)
df <- d$data
n_categories <- d$ncat
################ Format Data ###########################
data_formatter <- function(df) {
categories <- df["category_id"]
x <- df["elapsed_duration"]
x["identical_brands"] <- asinh(df$identical_brands)
x["brand_name_counts"] <- asinh(df$brand_name_count)
x["h_sdi_val"] <- asinh(df$h_sdi_val)
x["hm_sdi_val"] <- asinh(df$hm_sdi_val)
x["m_sdi_val"] <- asinh(df$m_sdi_val)
x["lm_sdi_val"] <- asinh(df$lm_sdi_val)
x["l_sdi_val"] <- asinh(df$l_sdi_val)
#interaction terms for competitors
x["ib*elapsed"] <- x["elapsed_duration"]*x["identical_brands"]
x["bnc*elapsed"] <- x["elapsed_duration"] * x["brand_name_counts"]
y <- ifelse(df["final_status"]=="Terminated",1,0)
return(list(x=x,y=y))
}
train <- data_formatter(df)
categories <- df$category_id
x <- train$x
y <- train$y
```
### Intervention: Adding a single competitor
```{r}
inherited_cols <- c(
"elapsed_duration"
,"identical_brands"
,"brand_name_counts"
,"h_sdi_val"
,"hm_sdi_val"
,"m_sdi_val"
,"lm_sdi_val"
,"l_sdi_val"
,"status_NYR"
,"status_EBI"
,"status_ANR"
,"ib*elapsed"
,"bnc*elapsed"
)
```
#### Generics
```{r}
#generics intervention
brand_intervention_ib <- x[inherited_cols]
brand_intervention_ib["identical_brands"] <- asinh(sinh(x$identical_brands)+1) #add a single generic brand
brand_intervention_ib["ib*elapsed"] <- brand_intervention_ib$identical_brands * brand_intervention_ib$elapsed_duration
```
```{r}
counterfact_marketing_ib <- list(
D = ncol(x),#
N = nrow(x),
L = n_categories$count,
y = as.vector(y),
ll = as.vector(categories),
x = as.matrix(x),
mu_mean = 0,
mu_stdev = 0.05,
sigma_shape = 4,
sigma_rate = 20,
Nx = nrow(x),
llx = as.vector(categories),
counterfact_x_tilde = as.matrix(brand_intervention_ib),
counterfact_x = as.matrix(x)
)
```
```{r}
generated_bi <- gqs(
fit@stanmodel,
data=counterfact_marketing_ib,
draws=as.matrix(fit),
seed=11021585
)
```
### USP DC
```{r}
#formulary intervention
brand_intervention_bnc <- x[c(inherited_cols,"identical_brands","ib*elapsed")]
brand_intervention_bnc["brand_name_counts"] <- asinh(sinh(x$brand_name_counts)+1) #add a single formulary competitor brand
brand_intervention_bnc["bnc*elapsed"] <- brand_intervention_bnc$brand_name_counts * brand_intervention_bnc$elapsed_duration
```
```{r}
counterfact_marketing_bnc <- list(
D = ncol(x),#
N = nrow(x),
L = n_categories$count,
y = as.vector(y),
ll = as.vector(categories),
x = as.matrix(x),
mu_mean = 0,
mu_stdev = 0.05,
sigma_shape = 4,
sigma_rate = 20,
Nx = nrow(x),
llx = as.vector(categories),
counterfact_x_tilde = as.matrix(brand_intervention_bnc),
counterfact_x = as.matrix(x)
)
```
```{r}
generated_bnc <- gqs(
fit@stanmodel,
data=counterfact_marketing_bnc,
draws=as.matrix(fit),
seed=11021585
)
```
# Fit Model
```{r}
################################# FIT MODEL #########################################
fit <- stan(
file='Hierarchal_Logistic.stan',
data = counterfact_marketing_ib,
chains = 4,
iter = 5000,
seed = 11021585
)
```
```{r}
hist(as.vector(extract(generated, pars="p_prior")$p_prior))
hist(as.vector(extract(generated, pars="mu_prior")$mu_prior), )
hist(as.vector(extract(generated, pars="sigma_prior")$sigma_prior))
```
```{r}
check_hmc_diagnostics(fit)
hist(as.vector(extract(generated, pars="p_predicted")$p_predicted))
```
# Diagnostics
```{r}
#trace plots
plot(fit, pars=c("mu"), plotfun="trace")
for (i in 1:4) {
print(
mcmc_rank_overlay(
fit,
pars=c(
paste0("mu[",4*i-3,"]"),
paste0("mu[",4*i-2,"]"),
paste0("mu[",4*i-1,"]"),
paste0("mu[",4*i,"]")
),
n_bins=100
)+ legend_move("top") +
scale_colour_ghibli_d("KikiMedium")
)
}
```
```{r}
plot(fit, pars=c("sigma"), plotfun="trace")
for (i in 1:4) {
print(
mcmc_rank_overlay(
fit,
pars=c(
paste0("sigma[",4*i-3,"]"),
paste0("sigma[",4*i-2,"]"),
paste0("sigma[",4*i-1,"]"),
paste0("sigma[",4*i,"]")
),
n_bins=100
)+ legend_move("top") +
scale_colour_ghibli_d("KikiMedium")
)
}
```
```{r}
#other diagnostics
logpost <- log_posterior(fit)
nuts_prmts <- nuts_params(fit)
posterior <- as.array(fit)
```
```{r}
color_scheme_set("darkgray")
div_style <- parcoord_style_np(div_color = "green", div_size = 0.05, div_alpha = 0.4)
mcmc_parcoord(posterior, regex_pars = "mu", np=nuts_prmts, np_style = div_style, alpha = 0.05)
```
```{r}
for (i in 1:4) {
mus = sapply(3:0, function(j) paste0("mu[",4*i-j ,"]"))
print(
mcmc_pairs(
posterior,
np = nuts_prmts,
pars=c(
mus,
"lp__"
),
off_diag_args = list(size = 0.75)
)
)
}
```
```{r}
mcmc_parcoord(posterior,regex_pars = "sigma", np=nuts_prmts, alpha=0.05)
```
```{r}
for (i in 1:4) {
params = sapply(3:0, function(j) paste0("sigma[",4*i-j ,"]"))
print(
mcmc_pairs(
posterior,
np = nuts_prmts,
pars=c(
params,
"lp__"
),
off_diag_args = list(size = 0.75)
)
)
}
```
```{r}
for (k in 1:22) {
for (i in 1:4) {
params = sapply(3:0, function(j) paste0("beta[",k,",",4*i-j ,"]"))
print(
mcmc_pairs(
posterior,
np = nuts_prmts,
pars=c(
params,
"lp__"
),
off_diag_args = list(size = 0.75)
)
)
}}
```
# Results
```{r}
################################# ANALYZE #####################################
print(fit)
```
## Result Plots
Note the regular large difference in variance.
I would guess those are the beta[1:22,2] values.
I wonder if a lot of the variance is due to the 2 values that are sitting out.
```{r}
beta_list <- list(
groups = c(
`1`="Infections & Parasites",
`2`="Neoplasms",
`3`="Blood & Immune system",
`4`="Endocrine, Nutritional, and Metabolic",
`5`="Mental & Behavioral",
`6`="Nervous System",
`7`="Eye and Adnexa",
`8`="Ear and Mastoid",
`9`="Circulatory",
`10`="Respiratory",
`11`="Digestive",
`12`="Skin & Subcutaneaous tissue",
`13`="Musculoskeletal",
`14`="Genitourinary",
`15`="Pregancy, Childbirth, & Puerperium",
`16`="Perinatal Period",
`17`="Congential",
`18`="Symptoms, Signs etc.",
`19`="Injury etc.",
`20`="External Causes",
`21`="Contact with Healthcare",
`22`="Special Purposes"
),
parameters = c(
`1`="Elapsed Duration",
# brands
`2`="asinh(Generic Brands)",
`3`="asinh(Competitors USPDC)",
# population
`4`="asinh(High SDI)",
`5`="asinh(High-Medium SDI)",
`6`="asinh(Medium SDI)",
`7`="asinh(Low-Medium SDI)",
`8`="asinh(Low SDI)",
#Status
`9`="status_NYR",
`10`="status_EBI",
`11`="status_ANR",
#interactions for brands
`12`="ib*elapsed",
`13`="bnc*elapsed",
# interactions for status
`14`="sNYR*elapsed",
`15`="sEBI*elapsed",
`16`="sANR*elapsed"
)
)
get_parameters <- function(stem,class_list) {
#get categories and lengths
named <- names(class_list)
lengths <- sapply(named, (function (x) length(class_list[[x]])))
#describe the grid needed
iter_list <- sapply(named, (function (x) 1:lengths[x]))
#generate the list of parameters
pardf <- generate_parameter_df(stem, iter_list)
#add columns with appropriate human-readable names
for (name in named) {
pardf[paste(name,"_hr",sep="")] <- as.factor(
sapply(pardf[name], (function (i) class_list[[name]][i]))
)
}
return(pardf)
}
generate_parameter_df <- function(stem, iter_list) {
grid <- expand.grid(iter_list)
grid["param_name"] <- grid %>% unite(x,colnames(grid),sep=",")
grid["param_name"] <- paste(stem,"[",grid$param_name,"]",sep="")
return(grid)
}
group_mcmc_areas <- function(
stem,# = "beta"
class_list,# = beta_list
stanfit,# = fit
group_id,# = 2
rename=TRUE
) {
#get all parameter names
params <- get_parameters(stem,class_list)
#filter down to parameters of interest
params <- filter(params,groups == group_id)
#Get dataframe with only the rows of interest
filtdata <- as.data.frame(stanfit)[params$param_name]
#rename columns
if (rename) dimnames(filtdata)[[2]] <- params$parameters_hr
#get group name for title
group_name <- class_list$groups[group_id]
#create area plot with appropriate title
mcmc_areas(filtdata,prob = 0.8, prob_outer = 0.95) +
ggtitle(paste("Parameter distributions for ICD-10 class:",group_name))
}
parameter_mcmc_areas <- function(
stem,# = "beta"
class_list,# = beta_list
stanfit,# = fit
parameter_id,# = 2
rename=TRUE
) {
#get all parameter names
params <- get_parameters(stem,class_list)
#filter down to parameters of interest
params <- filter(params,parameters == parameter_id)
#Get dataframe with only the rows of interest
filtdata <- as.data.frame(stanfit)[params$param_name]
#rename columns
if (rename) dimnames(filtdata)[[2]] <- params$groups_hr
#get group name for title
parameter_name <- class_list$parameters[parameter_id]
#create area plot with appropriate title
mcmc_areas(filtdata,prob = 0.8, prob_outer = 0.95) +
ggtitle(parameter_name,"Parameter Distribution")
}
```
```{r}
#mcmc_intervals(fit, pars=get_parameters("beta",beta_list)$param_name)
```
### Investigating parameter distributions
```{r}
#g1 <- group_mcmc_areas("beta",beta_list,fit,2)
#g2 <- group_mcmc_areas("beta",beta_list,fit,2)
#g3 <- group_mcmc_areas("beta",beta_list,fit,2)
#g4 <- group_mcmc_areas("beta",beta_list,fit,2)
#g5 <- group_mcmc_areas("beta",beta_list,fit,2)
#g6 <- group_mcmc_areas("beta",beta_list,fit,2)
#g7 <- group_mcmc_areas("beta",beta_list,fit,2)
#g8 <- group_mcmc_areas("beta",beta_list,fit,2)
#g9 <- group_mcmc_areas("beta",beta_list,fit,2)
#g10 <- group_mcmc_areas("beta",beta_list,fit,2)
#g11 <- group_mcmc_areas("beta",beta_list,fit,2)
#g12 <- group_mcmc_areas("beta",beta_list,fit,2)
#g13 <- group_mcmc_areas("beta",beta_list,fit,2)
#g14 <- group_mcmc_areas("beta",beta_list,fit,2)
#g15 <- group_mcmc_areas("beta",beta_list,fit,2)
#g16 <- group_mcmc_areas("beta",beta_list,fit,2)
#g17 <- group_mcmc_areas("beta",beta_list,fit,2)
#g18 <- group_mcmc_areas("beta",beta_list,fit,2)
#g19 <- group_mcmc_areas("beta",beta_list,fit,2)
#g20 <- group_mcmc_areas("beta",beta_list,fit,2)
#g21 <- group_mcmc_areas("beta",beta_list,fit,2)
#g22 <- group_mcmc_areas("beta",beta_list,fit,2)
p1 <- parameter_mcmc_areas("beta",beta_list,fit,1)
p2 <- parameter_mcmc_areas("beta",beta_list,fit,2)
p3 <- parameter_mcmc_areas("beta",beta_list,fit,3)
#p4 <- parameter_mcmc_areas("beta",beta_list,fit,4)
#p5 <- parameter_mcmc_areas("beta",beta_list,fit,5)
#p6 <- parameter_mcmc_areas("beta",beta_list,fit,6)
#p7 <- parameter_mcmc_areas("beta",beta_list,fit,7)
#p8 <- parameter_mcmc_areas("beta",beta_list,fit,8)
p9 <- parameter_mcmc_areas("beta",beta_list,fit,9)
p10 <- parameter_mcmc_areas("beta",beta_list,fit,10)
p11 <- parameter_mcmc_areas("beta",beta_list,fit,11)
p12 <- parameter_mcmc_areas("beta",beta_list,fit,12)
p13 <- parameter_mcmc_areas("beta",beta_list,fit,13)
p14 <- parameter_mcmc_areas("beta",beta_list,fit,14)
p15 <- parameter_mcmc_areas("beta",beta_list,fit,15)
p16 <- parameter_mcmc_areas("beta",beta_list,fit,16)
```
Note these have 95% outer CI and 80% inner (shaded)
1) "Elapsed Duration",
2) "asinh(Generic Brands)",
3) "asinh(Competitors USPDC)",
4) "asinh(High SDI)",
5) "asinh(High-Medium SDI)",
6) "asinh(Medium SDI)",
7) "asinh(Low-Medium SDI)",
8) "asinh(Low SDI)",
9) "status_NYR",
10) "status_EBI",
11) "status_ANR",
12) "ib*elapsed",
13) "bnc*elapsed",
14) "sNYR*elapsed",
15) "sEBI*elapsed",
16) "sANR*elapsed"
of interest
- p1 + p2
- p3 + p2
- p2 + p12
- p3 + p13
- p9 + p14
- p10 + p15
- p11 + p16
```{r}
p1 + p2
```
```{r}
p2 + p3
```
```{r}
p2 + p12
```
```{r}
p3 + p13
```
```{r}
p9 + p14
```
```{r}
p10 + p15
```
```{r}
p11 + p16
```
# Posterior Prediction
```{r}
#TODO: Convert to ggplot, stabilize y axis
hist(as.vector(extract(generated, pars="p_predicted_default")$p_predicted_default))
hist(as.vector(extract(generated, pars="p_predicted_intervention")$p_predicted_intervention))
```
## Distribution of Predicted Differences
### Intervention: Adding a single competitor
#### Generics
```{r}
#TODO: Convert to ggplot, stabilize y axis
hist(as.vector(extract(generated_ib, pars="p_predicted_default")$p_predicted_default), bins=100)
hist(as.vector(extract(generated_ib, pars="p_predicted_intervention")$p_predicted_intervention), bins=100)
hist(as.vector(extract(generated_ib, pars="predicted_difference")$predicted_difference), bins=100)
```
```{r}
pddf_ib <- data.frame(extract(generated_ib, pars="predicted_difference")$predicted_difference) |>
pivot_longer(X1:X1343)
#TODO: Fix Category names
pddf_ib["entry_idx"] <- as.numeric(gsub("\\D","",pddf_ib$name))
pddf_ib["category"] <- sapply(pddf_ib$entry_idx, function(i) df$category_id[i])
pddf_ib["category_name"] <- sapply(pddf_ib$category, function(i) beta_list$groups[i])
```
```{r}
ggplot(pddf_ib, aes(x=value,)) +
geom_histogram(bins=100) +
labs(
title = "Distribution of predicted differences"
,x = "Difference in probability due to intervention"
,y = "Predicted counts"
) +
#xlim(-0.3,0.1) +
geom_vline(aes(xintercept = 0), color = "skyblue", linetype="dashed")
ggplot(pddf_ib, aes(x=value,)) +
geom_histogram(bins=100) +
facet_wrap(
~factor(
category_name,
levels=beta_list$groups
)
, labeller = label_wrap_gen(multi_line = TRUE)
, ncol=5) +
labs(
title = "Distribution of predicted differences",
subtitle = "By group"
,x = "Difference in probability due to intervention"
,y = "Predicted counts"
) +
#xlim(-0.25,0.1) +
geom_vline(aes(xintercept = 0), color = "skyblue", linetype="dashed") +
theme(strip.text.x = element_text(size = 8))
```
#### USP DC
```{r}
#TODO: Convert to ggplot, stabilize y axis
hist(as.vector(extract(generated_bnc, pars="p_predicted_default")$p_predicted_default), bins=100)
hist(as.vector(extract(generated_bnc, pars="p_predicted_intervention")$p_predicted_intervention), bins=100)
hist(as.vector(extract(generated_bnc, pars="predicted_difference")$predicted_difference), bins=100)
```
```{r}
pddf_bnc <- data.frame(extract(generated_bnc, pars="predicted_difference")$predicted_difference) |>
pivot_longer(X1:X1343)
#Add Category names
pddf_bnc["entry_idx"] <- as.numeric(gsub("\\D","",pddf_bnc$name))
pddf_bnc["category"] <- sapply(pddf_bnc$entry_idx, function(i) df$category_id[i])
pddf_bnc["category_name"] <- sapply(pddf_bnc$category, function(i) beta_list$groups[i])
#add snapshot date
pddf_bnc["snapshot_date"] <- sapply(pddf_bnc$entry_idx, function(i) as_date(df$earliest_date_observed[i]))
```
```{r}
ggplot(pddf_bnc, aes(x=value,)) +
geom_histogram(bins=100) +
labs(
title = "Distribution of predicted differences"
,x = "Difference in probability due to intervention"
,y = "Predicted counts"
) +
#xlim(-0.3,0.1) +
geom_vline(aes(xintercept = 0), color = "skyblue", linetype="dashed")
ggplot(pddf_bnc, aes(x=value,)) +
geom_histogram(bins=100) +
facet_wrap(
~factor(
category_name,
levels=beta_list$groups
)
, labeller = label_wrap_gen(multi_line = TRUE)
, ncol=5) +
labs(
title = "Distribution of predicted differences",
subtitle = "By group"
,x = "Difference in probability due to intervention"
,y = "Predicted counts"
) +
#xlim(-0.25,0.1) +
geom_vline(aes(xintercept = 0), color = "skyblue", linetype="dashed") +
theme(strip.text.x = element_text(size = 8))
```

@ -1,239 +0,0 @@
library(bayesplot)
available_mcmc(pattern = "_nuts_")
library(ggplot2)
library(posterior)
library(cmdstanr)
library(rstan) # for stanfit
#Resources: https://github.com/stan-dev/rstan/wiki/RStan-Getting-Started
#save unchanged models instead of recompiling
rstan_options(auto_write = TRUE)
#allow for multithreaded sampling
options(mc.cores = parallel::detectCores())
#test installation, shouldn't get any errors
#example(stan_model, package = "rstan", run.dontrun = TRUE)
################ Pull data from database ######################
library(RPostgreSQL)
driver <- dbDriver("PostgreSQL")
con <- dbConnect(
driver,
user='root',
password='root',
dbname='aact_db',
host='will-office'
)
query <- dbSendQuery(
con,
"select * from formatted_data_with_planned_enrollment;"
)
df <- fetch(query,Inf)
df <- na.omit(df)
n_categories <- 22 #number of categories in ICD-10
################ Format Data ###########################
categories <- df["category_id"]
#Convert log(x+1) to arcsinh
x <- df["elapsed_duration"]
x["log_n_brands"] <- log(df$n_brands + 1)
x["h_sdi_val"] <- log(df$h_sdi_val + 1)
x["hm_sdi_val"] <- log(df$hm_sdi_val + 1)
x["m_sdi_val"] <- log(df$m_sdi_val + 1)
x["lm_sdi_val"] <- log(df$lm_sdi_val + 1)
x["l_sdi_val"] <- log(df$l_sdi_val + 1)
#x["enrollment"] <- df["current_enrollment"] / df["planned_enrollment"]
#square terms
#x["enrollment^2"] <- x["enrollment"]^2
#x["elapsed_duration^2"] <- x["elapsed_duration"]^2
#x["n_brands^2"] <- x["n_brands"]^2
#break out
x["status_NYR"] <- ifelse(df["current_status"]=="Not yet recruiting",1,0)
x["status_Rec"] <- ifelse(df["current_status"]=="Recruiting",1,0)
x["status_ANR"] <- ifelse(df["current_status"]=="Active, not recruiting",1,0)
x["status_EBI"] <- ifelse(df["current_status"]=="Enrolling by invitation",1,0)
y <- ifelse(df["final_status"]=="Terminated",1,0)
################################# DATA EXPLORATION ############################
#Plot terminated vs completed
#Plot duration for terminated vs completed
#Plot different times of
################################# FIT #########################################
#setup data (named list)
trials_data <- list(
D = ncol(x),#
N = nrow(x),
L = n_categories,
y = as.vector(y),
ll = categories$category_id,
x = as.matrix(x),
mu_mean = 0,
mu_stdev = 0.5,
sigma_shape = 6,
sigma_rate = 12
)
model <- cmdstan_model(file.path("Hierarchal_Logistic.stan"))
fit <- model$sample(
data = trials_data,
seed = 11021585,
chains = 4,
parallel_chains = 4,
refresh = 500
)
################################# ANALYZE #####################################
color_scheme_set("darkgray")
div_style <- parcoord_style_np(div_color = "green", div_size = 0.05, div_alpha = 0.4)
print(fit$summary(),n=265)
stanfitted <- rstan::read_stan_csv(fit$output_files())
#analyze mu values
draw_mu <- fit$draws("mu")
mcmc_hist(draw_mu)
mcmc_trace(draw_mu)
mcmc_pairs(draw_mu)
mcmc_parcoord(posterior,pars=c(
"mu[1]",
"mu[2]",
"mu[3]",
"mu[4]",
"mu[5]",
"mu[6]",
"mu[7]",
"mu[8]",
"mu[9]",
"mu[10]",
"mu[11]"
),
np=nuts_prmts,
np_style = div_style
)
#check sigma
draw_sigma <- fit$draws("sigma")
mcmc_hist(draw_sigma)
mcmc_trace(draw_sigma)
mcmc_parcoord(posterior,pars=c(
"sigma[1]",
"sigma[2]",
"sigma[3]",
"sigma[4]",
"sigma[5]",
"sigma[6]",
"sigma[7]",
"sigma[8]",
"sigma[9]",
"sigma[10]",
"sigma[11]"
),
np=nuts_prmts,
np_style = div_style
)
#other diagnostics
logpost <- log_posterior(fit)
nuts_prmts <- nuts_params(fit)
posterior <- fit$draws()
mcmc_pairs(
posterior,
np = nuts_prmts,
pars=c(
"mu[1]",
"mu[2]",
"mu[3]",
"mu[4]",
"mu[5]",
"mu[6]",
"mu[7]",
"mu[8]",
"mu[9]",
"mu[10]",
"mu[11]"
),
off_diag_args = list(size = 0.75)
)
#Interpretation
mcmc_areas(posterior,
pars=c(
"mu[1]",
"mu[2]",
"mu[3]",
"mu[4]",
"mu[5]",
"mu[6]",
"mu[7]",
"mu[8]",
"mu[9]",
"mu[10]",
"mu[11]"
),
prob = 0.95
)
#Interpretation
mcmc_areas(posterior,
pars=c(
"sigma[1]",
"sigma[2]",
"sigma[3]",
"sigma[4]",
"sigma[5]",
"sigma[6]",
"sigma[7]",
"sigma[8]",
"sigma[9]",
"sigma[10]",
"sigma[11]"
),
prob = 0.95
)
#iterate through betas
mcmc_areas(posterior,
pars=c(
"beta[1,*]"
),
prob = 0.95
)
#generate array of betas
betas_array <- sapply(1:11, function(param) sapply(1:22, function(group) paste0("beta[",group,",",param,"]")))
for (group in 1:22) {
print(
mcmc_areas(posterior,
pars=betas_array[group,],
prob = 0.95
)
)
}
for (param in 1:11) {
print(
mcmc_areas(posterior,
pars=betas_array[,param],
prob = 0.95
)
)
}

@ -19,13 +19,15 @@ data {
array[N] row_vector[D] x; // independent variables array[N] row_vector[D] x; // independent variables
real mu_mean; //hyperprior real mu_mean; //hyperprior
real<lower=0> mu_stdev; //hyperprior real<lower=0> mu_stdev; //hyperprior
real sigma_shape; //hyperprior real sigma_location; //hyperprior
real sigma_rate; //hyperprior real<lower=0> sigma_scale; //hyperprior
//counterfactuals //counterfactuals
int<lower=0> Nx; int<lower=0> Nx;
array[Nx] int<lower=1, upper=L> llx; array[Nx] int<lower=1, upper=L> llx;//vec of categories
array[Nx] row_vector[D] counterfact_x_tilde; // Posterior Prediction intervention array[Nx] row_vector[D] counterfact_x_tilde; // Posterior Prediction intervention
array[Nx] row_vector[D] counterfact_x; // Posterior Prediction intervention array[Nx] row_vector[D] counterfact_x; // Posterior Prediction intervention
//the two statuses to catch relative difference
array[2] int status_indexes; //the two status indexes to compare (order is x[1] - x[2])
} }
parameters { parameters {
array[D] real mu; array[D] real mu;
@ -33,7 +35,7 @@ parameters {
array[L] vector[D] beta; array[L] vector[D] beta;
} }
model { model {
sigma ~ gamma(sigma_shape,sigma_rate); //hyperprior for stdev: shape and inverse scale sigma ~ lognormal(sigma_location,sigma_scale); //hyperprior for stdev: shape and inverse scale
mu ~ normal(mu_mean, mu_stdev); //hyperprior for mean //TODO: convert to mvnormal mu ~ normal(mu_mean, mu_stdev); //hyperprior for mean //TODO: convert to mvnormal
for (l in 1:L) { for (l in 1:L) {
beta[l] ~ normal(mu, sigma); beta[l] ~ normal(mu, sigma);
@ -58,13 +60,20 @@ generated quantities {
real p_predicted_intervention[Nx]; //predicted p_values real p_predicted_intervention[Nx]; //predicted p_values
real predicted_difference[Nx]; //difference in predicted values real predicted_difference[Nx]; //difference in predicted values
//collect array of relative status differences between
array[L] real status_diff;
//GENERATE RELATIVE DIFFERENCES BETWEEN STATUSES
for (l in 1:L) {
status_diff[l] = beta[l,status_indexes[1]] - beta[l,status_indexes[2]];
}
//GENERATE PRIOR PREDICTIONS //GENERATE PRIOR PREDICTIONS
{ {
vector[D] beta_prior[L];//local var vector[D] beta_prior[L];//local var
//sample parameters //sample parameters
for (d in 1:D) { for (d in 1:D) {
mu_prior[d] = normal_rng(mu_mean,mu_stdev); mu_prior[d] = normal_rng(mu_mean,mu_stdev);
sigma_prior[d] = gamma_rng(sigma_shape,sigma_rate); sigma_prior[d] = lognormal_rng(sigma_location,sigma_scale);
} }
for (l in 1:L) { for (l in 1:L) {
for (d in 1:D) { for (d in 1:D) {
@ -87,6 +96,7 @@ generated quantities {
p_predicted_default[n] = inv_logit( counterfact_x[n] * beta[llx[n]] ); p_predicted_default[n] = inv_logit( counterfact_x[n] * beta[llx[n]] );
p_predicted_intervention[n] = inv_logit( counterfact_x_tilde[n] * beta[llx[n]] ); //intervention p_predicted_intervention[n] = inv_logit( counterfact_x_tilde[n] * beta[llx[n]] ); //intervention
predicted_difference[n] = p_predicted_default[n] - p_predicted_intervention[n]; //intervention - base case
predicted_difference[n] = p_predicted_intervention[n] - p_predicted_default[n];
} }
} }

@ -1,30 +0,0 @@
//
// This Stan program defines a simple model, with a
// vector of values 'y' modeled as normally distributed
// with mean 'mu' and standard deviation 'sigma'.
//
// Learn more about model development with Stan at:
//
// http://mc-stan.org/users/interfaces/rstan.html
// https://github.com/stan-dev/rstan/wiki/RStan-Getting-Started
//
// The input data is a vector 'y' of length 'N'.
data {
int<lower=1> D;
int<lower=1> N;
int<lower=0, upper=1> y[N];
row_vector[D] x[N];
}
parameters {
real mu[D];
real<lower=0> sigma[D];
}
model {
sigma ~ gamma(2,0.1);
mu ~ normal(0, sigma); //convert to mvnormal
for (n in 1:N) {
y[n] ~ bernoulli_logit(x[n] * mu);
}
}

@ -1,32 +0,0 @@
//
// This Stan program defines a simple model, with a
// vector of values 'y' modeled as normally distributed
// with mean 'mu' and standard deviation 'sigma'.
//
// Learn more about model development with Stan at:
//
// http://mc-stan.org/users/interfaces/rstan.html
// https://github.com/stan-dev/rstan/wiki/RStan-Getting-Started
//
// The input data is a vector 'y' of length 'N'.
data {
int<lower=0> N;
int<lower=0> k;
matrix[N,k] X;
vector[N] int<lower=0, upper=1> y;
}
// The parameters accepted by the model. Our model
// accepts two parameters 'mu' and 'sigma'.
parameters {
vector[k] beta;
}
// The model to be estimated. We model the output
// 'y' to be normally distributed with mean 'mu'
// and standard deviation 'sigma'.
model {
y ~ bernoulli_logit( X * beta);
}

@ -0,0 +1,34 @@
% latex table generated in R 4.4.2 by xtable 1.8-4 package
% Sun Feb 2 01:37:36 2025
\begin{table}[ht]
\centering
\begin{tabular}{lrrrrrrrrr}
\hline
ICD-10 Category & mean & P(≥0) & 2.5\% & 5\% & 25\% & 50\% median & 75\% & 95\% & 97.5\% \\
\hline
Blood \& Immune system & 0.061 & 0.624 & -0.333 & -0.267 & -0.071 & 0.061 & 0.194 & 0.388 & 0.454 \\
Circulatory & 0.037 & 0.577 & -0.362 & -0.293 & -0.094 & 0.038 & 0.170 & 0.363 & 0.426 \\
Congential & 0.063 & 0.628 & -0.332 & -0.264 & -0.068 & 0.063 & 0.195 & 0.391 & 0.456 \\
Contact with Healthcare & 0.063 & 0.627 & -0.335 & -0.267 & -0.070 & 0.064 & 0.194 & 0.390 & 0.454 \\
Digestive & 0.060 & 0.621 & -0.339 & -0.270 & -0.071 & 0.059 & 0.192 & 0.388 & 0.454 \\
Ear and Mastoid & 0.063 & 0.625 & -0.332 & -0.263 & -0.069 & 0.064 & 0.196 & 0.393 & 0.457 \\
Endocrine, Nutritional, and Metabolic & 0.177 & 0.820 & -0.201 & -0.137 & 0.045 & 0.173 & 0.304 & 0.505 & 0.573 \\
External Causes & 0.063 & 0.625 & -0.330 & -0.266 & -0.070 & 0.064 & 0.194 & 0.392 & 0.460 \\
Eye and Adnexa & 0.061 & 0.624 & -0.333 & -0.265 & -0.069 & 0.062 & 0.192 & 0.386 & 0.452 \\
Genitourinary & 0.063 & 0.627 & -0.337 & -0.270 & -0.070 & 0.065 & 0.195 & 0.389 & 0.456 \\
Infections \& Parasites & 0.135 & 0.772 & -0.223 & -0.163 & 0.013 & 0.134 & 0.257 & 0.438 & 0.498 \\
Injury etc. & 0.063 & 0.625 & -0.337 & -0.268 & -0.069 & 0.062 & 0.196 & 0.392 & 0.459 \\
Mental \& Behavioral & 0.142 & 0.767 & -0.239 & -0.175 & 0.010 & 0.140 & 0.270 & 0.469 & 0.537 \\
Musculoskeletal & 0.159 & 0.794 & -0.218 & -0.156 & 0.027 & 0.156 & 0.286 & 0.482 & 0.550 \\
Neoplasms & 0.211 & 0.902 & -0.107 & -0.056 & 0.099 & 0.208 & 0.320 & 0.489 & 0.546 \\
Nervous System & 0.009 & 0.524 & -0.383 & -0.315 & -0.120 & 0.011 & 0.140 & 0.327 & 0.389 \\
Perinatal Period & 0.062 & 0.626 & -0.338 & -0.270 & -0.068 & 0.062 & 0.194 & 0.390 & 0.457 \\
Pregancy, Childbirth, \& Puerperium & 0.061 & 0.622 & -0.336 & -0.270 & -0.071 & 0.061 & 0.194 & 0.392 & 0.458 \\
Respiratory & 0.061 & 0.622 & -0.335 & -0.269 & -0.072 & 0.061 & 0.195 & 0.391 & 0.458 \\
Skin \& Subcutaneaous tissue & 0.104 & 0.704 & -0.283 & -0.220 & -0.027 & 0.103 & 0.234 & 0.429 & 0.494 \\
Special Purposes & 0.062 & 0.625 & -0.335 & -0.268 & -0.070 & 0.062 & 0.194 & 0.391 & 0.456 \\
Symptoms, Signs etc. & 0.062 & 0.625 & -0.332 & -0.265 & -0.069 & 0.062 & 0.194 & 0.390 & 0.456 \\
\hline
\end{tabular}
\end{table}

@ -0,0 +1,10 @@
c("Blood & Immune system", "Circulatory", "Congential", "Contact with Healthcare", "Digestive", "Ear and Mastoid", "Endocrine, Nutritional, and Metabolic", "External Causes", "Eye and Adnexa", "Genitourinary", "Infections & Parasites", "Injury etc.", "Mental & Behavioral", "Musculoskeletal", "Neoplasms", "Nervous System", "Perinatal Period", "Pregancy, Childbirth, & Puerperium", "Respiratory", "Skin & Subcutaneaous tissue", "Special Purposes", "Symptoms, Signs etc.")
c(-0.00287140656905416, -0.0020229135961933, -0.00252250078632693, -0.00209236160817254, -0.00233302952373521, -0.00216616648896081, -0.00681543732790809, -0.00273617241938979, -0.00219896995482389, -0.00310971192809426, -0.00900529540694934, -0.00252589644802287, -0.00444905498743218, -0.00275503221432378, -0.00295173909211749, -0.00517241124667845, -0.00201260276746087, -0.00257497154836192, -0.00242272398017638, -0.00267620974013439, -0.00248385412497201, -0.00206395314166231)
c(`2.5%` = -0.275944463803495, `2.5%` = -0.272921161056328, `2.5%` = -0.272430725186905, `2.5%` = -0.272911375314851, `2.5%` = -0.27286212768348, `2.5%` = -0.276406977245084, `2.5%` = -0.277987677303119, `2.5%` = -0.270429258845101, `2.5%` = -0.272173859797933, `2.5%` = -0.270957011640022, `2.5%` = -0.281051472827658, `2.5%` = -0.274123164780341, `2.5%` = -0.273927630545993, `2.5%` = -0.272259113214428, `2.5%` = -0.271867873121147, `2.5%` = -0.275526164264352, `2.5%` = -0.275736741086972, `2.5%` = -0.274025059638234,
`2.5%` = -0.271895651649722, `2.5%` = -0.274439135854432, `2.5%` = -0.272777026543343, `2.5%` = -0.274505781494588)
c(`97.5%` = 0.268525663885088, `97.5%` = 0.269687555821123, `97.5%` = 0.263988376114375, `97.5%` = 0.268376674723849, `97.5%` = 0.271595831106391, `97.5%` = 0.27398054865504, `97.5%` = 0.26497995981819, `97.5%` = 0.264914777867797, `97.5%` = 0.268729163024419, `97.5%` = 0.266687930004995, `97.5%` = 0.260632526818398, `97.5%` = 0.270701536658997, `97.5%` = 0.264287404395679, `97.5%` = 0.266631371530776, `97.5%` = 0.265171319133342, `97.5%` = 0.267696135908434, `97.5%` = 0.269792405742312, `97.5%` = 0.267738792080357,
`97.5%` = 0.270026733830649, `97.5%` = 0.267892275489918, `97.5%` = 0.266305005411752, `97.5%` = 0.271501986023693)
c(`5%` = -0.228422342352796, `5%` = -0.225192615705392, `5%` = -0.225155935562034, `5%` = -0.227577347541465, `5%` = -0.226336678780408, `5%` = -0.227963356496732, `5%` = -0.230488468962024, `5%` = -0.226216509362732, `5%` = -0.224813386072165, `5%` = -0.224824888562106, `5%` = -0.232874112114568, `5%` = -0.227479714082238, `5%` = -0.227858560023144, `5%` = -0.22530608055078, `5%` = -0.226179910621409, `5%` = -0.228284369418676, `5%` = -0.228444224989461, `5%` = -0.226622261032726, `5%` = -0.224288571128251,
`5%` = -0.227590395464131, `5%` = -0.225531022618535, `5%` = -0.227689137616937)
c(`95%` = 0.2234974899362, `95%` = 0.222074828728455, `95%` = 0.218357594565282, `95%` = 0.22222430007764, `95%` = 0.222289991457749, `95%` = 0.223327488400761, `95%` = 0.216270931014924, `95%` = 0.220095617146775, `95%` = 0.221009192368411, `95%` = 0.218989193656767, `95%` = 0.213804656879867, `95%` = 0.222889299900387, `95%` = 0.220133939553423, `95%` = 0.21899037055656, `95%` = 0.218796743068272, `95%` = 0.220217569663176, `95%` = 0.224044557893232, `95%` = 0.220936167501407, `95%` = 0.222159099161132,
`95%` = 0.220911069519647, `95%` = 0.220781640962889, `95%` = 0.223599356920508)

@ -0,0 +1,10 @@
c("Blood & Immune system", "Circulatory", "Congential", "Contact with Healthcare", "Digestive", "Ear and Mastoid", "Endocrine, Nutritional, and Metabolic", "External Causes", "Eye and Adnexa", "Genitourinary", "Infections & Parasites", "Injury etc.", "Mental & Behavioral", "Musculoskeletal", "Neoplasms", "Nervous System", "Perinatal Period", "Pregancy, Childbirth, & Puerperium", "Respiratory", "Skin & Subcutaneaous tissue", "Special Purposes", "Symptoms, Signs etc.")
c(0.00652882287222823, -0.0121276026193075, 0.00806097077518296, 0.00921072076176892, 0.00511136013511625, 0.00923452323640744, 0.0756452851959799, 0.00901967004583639, 0.00596509106734287, 0.00869308015726206, 0.0234704825434495, 0.00891347968211811, 0.0410008650026277, 0.0493113026890666, -0.0318651891745962, -0.0230137010884716, 0.00907668265519354, 0.0082773304353959, 0.00672386515176627, 0.0229027326955782, 0.00903950397151059, 0.00840626979762671)
c(`2.5%` = -0.26412401679988, `2.5%` = -0.284982548735974, `2.5%` = -0.262583809560454, `2.5%` = -0.259623047912961, `2.5%` = -0.267223017905891, `2.5%` = -0.262824783073146, `2.5%` = -0.182738362310984, `2.5%` = -0.261194421023313, `2.5%` = -0.264838971088612, `2.5%` = -0.263984097470059, `2.5%` = -0.233328888684629, `2.5%` = -0.260381735988535, `2.5%` = -0.219982381931615, `2.5%` = -0.209178899422793, `2.5%` = -0.272496159194591, `2.5%` = -0.293189864865698, `2.5%` = -0.259442015177563, `2.5%` = -0.265643699376373,
`2.5%` = -0.264848607612733, `2.5%` = -0.243262927814473, `2.5%` = -0.263583321279326, `2.5%` = -0.260710033426863)
c(`97.5%` = 0.279506924359323, `97.5%` = 0.25166727687992, `97.5%` = 0.279367210952163, `97.5%` = 0.278659096264822, `97.5%` = 0.274044451638933, `97.5%` = 0.280562384576216, `97.5%` = 0.359198759844572, `97.5%` = 0.282464614440408, `97.5%` = 0.274146522142649, `97.5%` = 0.279840596472466, `97.5%` = 0.282219317765516, `97.5%` = 0.279650795194328, `97.5%` = 0.3146382824935, `97.5%` = 0.324504387608479, `97.5%` = 0.198395249398707, `97.5%` = 0.238015436387141, `97.5%` = 0.279664049019525, `97.5%` = 0.282472259620116,
`97.5%` = 0.280170359985892, `97.5%` = 0.296090615801029, `97.5%` = 0.278827396276502, `97.5%` = 0.276519814652463)
c(`5%` = -0.217405377189081, `5%` = -0.235700053008877, `5%` = -0.215580888141684, `5%` = -0.212836780879927, `5%` = -0.220927862811969, `5%` = -0.215245283188846, `5%` = -0.139947007794807, `5%` = -0.214372400370517, `5%` = -0.216692707544591, `5%` = -0.215840640492215, `5%` = -0.190195428873606, `5%` = -0.214974248730335, `5%` = -0.175242262948575, `5%` = -0.166101667860902, `5%` = -0.228981038446028, `5%` = -0.246615923137647, `5%` = -0.214004181031889, `5%` = -0.218493362752846, `5%` = -0.21829426001738,
`5%` = -0.197184265526973, `5%` = -0.216831943794109, `5%` = -0.21336683632312)
c(`95%` = 0.231060746721114, `95%` = 0.206639994505824, `95%` = 0.232261579219567, `95%` = 0.231058781781102, `95%` = 0.228526975656424, `95%` = 0.233653720301541, `95%` = 0.306122759153545, `95%` = 0.234530990151044, `95%` = 0.226800701259279, `95%` = 0.230966741806046, `95%` = 0.237452575327, `95%` = 0.23322865073513, `95%` = 0.264306220644107, `95%` = 0.274559112084226, `95%` = 0.161143364484194, `95%` = 0.195044859439803, `95%` = 0.232513302970324, `95%` = 0.233960896032084, `95%` = 0.232756864140852,
`95%` = 0.246925692056239, `95%` = 0.231685551132494, `95%` = 0.230370019187908)

@ -0,0 +1,10 @@
c("Blood & Immune system", "Circulatory", "Congential", "Contact with Healthcare", "Digestive", "Ear and Mastoid", "Endocrine, Nutritional, and Metabolic", "External Causes", "Eye and Adnexa", "Genitourinary", "Infections & Parasites", "Injury etc.", "Mental & Behavioral", "Musculoskeletal", "Neoplasms", "Nervous System", "Perinatal Period", "Pregancy, Childbirth, & Puerperium", "Respiratory", "Skin & Subcutaneaous tissue", "Special Purposes", "Symptoms, Signs etc.")
c(-0.0543082831893662, -0.0491179148659016, -0.0550797452225853, -0.0532946953959887, -0.0546326964547788, -0.054263670489829, -0.101183732558573, -0.0537419015558274, -0.055296341966815, -0.0541521176630153, -0.111933746601916, -0.0536195743237358, -0.101358093383466, -0.109295568325447, -0.242704066590673, -0.0324576251191776, -0.0530684599999257, -0.0529707690770896, -0.0545919114607711, -0.0809466615050335, -0.0530673747164349, -0.0537090394695628)
c(`2.5%` = -0.3460926221197, `2.5%` = -0.340513734259116, `2.5%` = -0.345063660691308, `2.5%` = -0.343936968361375, `2.5%` = -0.347086498849369, `2.5%` = -0.346730664863283, `2.5%` = -0.402573667581036, `2.5%` = -0.344748248866169, `2.5%` = -0.348019495991554, `2.5%` = -0.343259904607912, `2.5%` = -0.397011060181461, `2.5%` = -0.347299904964005, `2.5%` = -0.398857333530158, `2.5%` = -0.407252271853641, `2.5%` = -0.543673509898535, `2.5%` = -0.315411836398564, `2.5%` = -0.344614905885746, `2.5%` = -0.345987208689716,
`2.5%` = -0.34467924126698, `2.5%` = -0.37464941870207, `2.5%` = -0.346982193867717, `2.5%` = -0.34255968704254)
c(`97.5%` = 0.23859370882391, `97.5%` = 0.247596369898235, `97.5%` = 0.236924146027621, `97.5%` = 0.239608837398885, `97.5%` = 0.23894631939739, `97.5%` = 0.238196795290067, `97.5%` = 0.180340815442861, `97.5%` = 0.240218974320717, `97.5%` = 0.235175513197134, `97.5%` = 0.237777766149638, `97.5%` = 0.156402075952097, `97.5%` = 0.242638519639189, `97.5%` = 0.182559370226462, `97.5%` = 0.170699887327904, `97.5%` = 0.0114150292406248, `97.5%` = 0.259944925352525, `97.5%` = 0.242795694071721, `97.5%` = 0.242602907693202,
`97.5%` = 0.239492781782234, `97.5%` = 0.204585540113804, `97.5%` = 0.238328250302865, `97.5%` = 0.240534823211121)
c(`5%` = -0.295316756003101, `5%` = -0.29096401042673, `5%` = -0.294243091294835, `5%` = -0.293355784827148, `5%` = -0.296193852536529, `5%` = -0.294348519148639, `5%` = -0.347024621453625, `5%` = -0.293279771169653, `5%` = -0.297136938616546, `5%` = -0.2933097076324, `5%` = -0.347474604177594, `5%` = -0.294318945943837, `5%` = -0.344628024841975, `5%` = -0.352532667961251, `5%` = -0.488379411138948, `5%` = -0.266550224886603, `5%` = -0.293396519481707, `5%` = -0.295913858425759, `5%` = -0.294475437187543,
`5%` = -0.322719512364534, `5%` = -0.294234511411049, `5%` = -0.291661527567577)
c(`95%` = 0.186170625673217, `95%` = 0.194446427538144, `95%` = 0.18316007227917, `95%` = 0.185398130082336, `95%` = 0.18656668417393, `95%` = 0.186918825584728, `95%` = 0.133329444707804, `95%` = 0.188140180351712, `95%` = 0.186846293810823, `95%` = 0.188406047073467, `95%` = 0.112535221760718, `95%` = 0.191176019972506, `95%` = 0.132004530075709, `95%` = 0.124477125901656, `95%` = -0.0267022930175043, `95%` = 0.205343484029368, `95%` = 0.187850282416095, `95%` = 0.190035921589226, `95%` = 0.188021330440522,
`95%` = 0.155090212003947, `95%` = 0.188333556494078, `95%` = 0.187492448246279)

@ -0,0 +1,10 @@
c("Blood & Immune system", "Circulatory", "Congential", "Contact with Healthcare", "Digestive", "Ear and Mastoid", "Endocrine, Nutritional, and Metabolic", "External Causes", "Eye and Adnexa", "Genitourinary", "Infections & Parasites", "Injury etc.", "Mental & Behavioral", "Musculoskeletal", "Neoplasms", "Nervous System", "Perinatal Period", "Pregancy, Childbirth, & Puerperium", "Respiratory", "Skin & Subcutaneaous tissue", "Special Purposes", "Symptoms, Signs etc.")
c(-0.0505321895701756, -0.0561236542390722, -0.0499660268658585, -0.0481574325504504, -0.0505967062178304, -0.0480668691756736, -0.0585983827703775, -0.047133883963608, -0.0507912436647474, -0.0478593490739956, -0.0816317285457012, -0.0482822682398582, -0.0774004055701482, -0.016726156695298, -0.315526037006588, -0.0578472700681722, -0.0475268941302727, -0.0480850373469818, -0.0494676291479126, -0.0931186973375372, -0.0479483938019099, -0.0486654863146441)
c(`2.5%` = -0.351333711658477, `2.5%` = -0.358192918691032, `2.5%` = -0.350165746673952, `2.5%` = -0.348260904879301, `2.5%` = -0.355213104294602, `2.5%` = -0.349537890844496, `2.5%` = -0.356636178298712, `2.5%` = -0.348967122811696, `2.5%` = -0.356770047469594, `2.5%` = -0.348523219782961, `2.5%` = -0.369067201876791, `2.5%` = -0.352751358464831, `2.5%` = -0.384222770661754, `2.5%` = -0.310459552529128, `2.5%` = -0.642054194627079, `2.5%` = -0.359167198818045, `2.5%` = -0.351037786426624, `2.5%` = -0.35686171619278,
`2.5%` = -0.353960823288628, `2.5%` = -0.398212841275992, `2.5%` = -0.351411960176182, `2.5%` = -0.352062830672535)
c(`97.5%` = 0.252996678658013, `97.5%` = 0.245199739323497, `97.5%` = 0.252568610015387, `97.5%` = 0.256300675128962, `97.5%` = 0.256220116158008, `97.5%` = 0.256880194696558, `97.5%` = 0.237496943950342, `97.5%` = 0.260731873495491, `97.5%` = 0.255694095814266, `97.5%` = 0.258199105421347, `97.5%` = 0.196240544658593, `97.5%` = 0.256780445660338, `97.5%` = 0.218570279154564, `97.5%` = 0.295751559042532, `97.5%` = -0.0498087194116947, `97.5%` = 0.238629751570793, `97.5%` = 0.258078396538427, `97.5%` = 0.259647869046876,
`97.5%` = 0.256663885447249, `97.5%` = 0.195728293212208, `97.5%` = 0.259664751280795, `97.5%` = 0.257403541589351)
c(`5%` = -0.29803422118825, `5%` = -0.304624731177692, `5%` = -0.298500654906565, `5%` = -0.295625102451718, `5%` = -0.300950367218894, `5%` = -0.296909500653078, `5%` = -0.304028644400323, `5%` = -0.295898014297575, `5%` = -0.301053900765771, `5%` = -0.297395770121559, `5%` = -0.318536205133514, `5%` = -0.298729047781782, `5%` = -0.328832973524529, `5%` = -0.260408972551825, `5%` = -0.580798660746861, `5%` = -0.303098555574414, `5%` = -0.297724180258084, `5%` = -0.300789071762739, `5%` = -0.29885389568916,
`5%` = -0.341186799958823, `5%` = -0.297555789883245, `5%` = -0.297336353504652)
c(`95%` = 0.199805705380915, `95%` = 0.193775727317953, `95%` = 0.20049984396355, `95%` = 0.203214802673669, `95%` = 0.202603902019158, `95%` = 0.203401989386427, `95%` = 0.187816936293634, `95%` = 0.205427481892033, `95%` = 0.200369696005793, `95%` = 0.203709821019864, `95%` = 0.149606773044668, `95%` = 0.201078718458991, `95%` = 0.168803960348435, `95%` = 0.23786658788661, `95%` = -0.0876108144400803, `95%` = 0.186931912303368, `95%` = 0.204472031901114, `95%` = 0.205112704275416, `95%` = 0.201106127451977,
`95%` = 0.145913702571692, `95%` = 0.204425554740135, `95%` = 0.202755710634796)

@ -0,0 +1,10 @@
c("Blood & Immune system", "Circulatory", "Congential", "Contact with Healthcare", "Digestive", "Ear and Mastoid", "Endocrine, Nutritional, and Metabolic", "External Causes", "Eye and Adnexa", "Genitourinary", "Infections & Parasites", "Injury etc.", "Mental & Behavioral", "Musculoskeletal", "Neoplasms", "Nervous System", "Perinatal Period", "Pregancy, Childbirth, & Puerperium", "Respiratory", "Skin & Subcutaneaous tissue", "Special Purposes", "Symptoms, Signs etc.")
c(-0.0374509867623648, -0.114801759701441, -0.0421991751741288, -0.0268927396537672, -0.0431305204973958, -0.0260913808525182, -0.147540114797909, -0.027116517230545, -0.0572148794918185, -0.0567196164994895, -0.0431781674057524, -0.0247442525263859, -0.148857275259831, 0.173176112299651, -0.745438348426778, 0.514928808041493, -0.0262970064646734, -0.0273698856833142, -0.0519713531203428, -0.0813059076860515, -0.0258722297716816, -0.0348374667962509)
c(`2.5%` = -0.519252573751591, `2.5%` = -0.588446720987112, `2.5%` = -0.518375863151681, `2.5%` = -0.504192330494074, `2.5%` = -0.521537560181517, `2.5%` = -0.501531706057096, `2.5%` = -0.605455988019874, `2.5%` = -0.50319865217871, `2.5%` = -0.529409792355877, `2.5%` = -0.537648621232678, `2.5%` = -0.392971765289971, `2.5%` = -0.499643963973294, `2.5%` = -0.654106115127152, `2.5%` = -0.223573014616573, `2.5%` = -1.12441685579914, `2.5%` = 0.0216592886163218, `2.5%` = -0.492165903236766, `2.5%` = -0.506906607161406,
`2.5%` = -0.530569224373654, `2.5%` = -0.560352091813988, `2.5%` = -0.502878744623734, `2.5%` = -0.516492014350377)
c(`97.5%` = 0.438156824615533, `97.5%` = 0.326892147498506, `97.5%` = 0.439646865645069, `97.5%` = 0.45479809614294, `97.5%` = 0.429980507934071, `97.5%` = 0.452354448697589, `97.5%` = 0.271710367913333, `97.5%` = 0.452356456142033, `97.5%` = 0.408657439741233, `97.5%` = 0.413237173559078, `97.5%` = 0.304781682760948, `97.5%` = 0.462872494668127, `97.5%` = 0.307321465786219, `97.5%` = 0.625146449622561, `97.5%` = -0.396240166662077, `97.5%` = 1.17318649525454, `97.5%` = 0.448797338514388, `97.5%` = 0.456641082563543,
`97.5%` = 0.416128814653975, `97.5%` = 0.375467600073314, `97.5%` = 0.455154502226114, `97.5%` = 0.445072841208461)
c(`5%` = -0.43284681982114, `5%` = -0.498779889626974, `5%` = -0.434007392588596, `5%` = -0.417440686797088, `5%` = -0.43620401741364, `5%` = -0.415561086942261, `5%` = -0.520616290327113, `5%` = -0.415868472350007, `5%` = -0.445215274649135, `5%` = -0.450348871660559, `5%` = -0.335854611911698, `5%` = -0.417370214498537, `5%` = -0.55799947646926, `5%` = -0.165197877092618, `5%` = -1.05984134753029, `5%` = 0.0851401986791414, `5%` = -0.412294843116399, `5%` = -0.421537839042216, `5%` = -0.443110847973097,
`5%` = -0.472054693822914, `5%` = -0.4154217625395, `5%` = -0.430050287469576)
c(`95%` = 0.353300713490598, `95%` = 0.251902327224973, `95%` = 0.353130963560884, `95%` = 0.367385797642419, `95%` = 0.346576238409847, `95%` = 0.364713198282056, `95%` = 0.20347262465658, `95%` = 0.366348980622731, `95%` = 0.328590570058774, `95%` = 0.329135185773538, `95%` = 0.24519101313148, `95%` = 0.372694013964094, `95%` = 0.231568717349548, `95%` = 0.544725565756189, `95%` = -0.449885315105183, `95%` = 1.03873143227049, `95%` = 0.364171369034129, `95%` = 0.369255306736876, `95%` = 0.335218886894626,
`95%` = 0.30207955992225, `95%` = 0.367493122771963, `95%` = 0.360231402349028)

@ -0,0 +1,10 @@
c("Blood & Immune system", "Circulatory", "Congential", "Contact with Healthcare", "Digestive", "Ear and Mastoid", "Endocrine, Nutritional, and Metabolic", "External Causes", "Eye and Adnexa", "Genitourinary", "Infections & Parasites", "Injury etc.", "Mental & Behavioral", "Musculoskeletal", "Neoplasms", "Nervous System", "Perinatal Period", "Pregancy, Childbirth, & Puerperium", "Respiratory", "Skin & Subcutaneaous tissue", "Special Purposes", "Symptoms, Signs etc.")
c(0.0177091826256191, -0.0174830982131017, 0.0197148498472504, 0.0267207484850693, 0.01865599931714, 0.0273355925564759, -0.0557624513358899, 0.0285704704444676, 0.0105781672515, 0.0120682740554864, 0.117270560237318, 0.0273743158412062, 0.0202098736769506, -0.0761301686125453, 0.14948178706425, 0.363548114620147, 0.027441418729276, 0.0271631725930479, 0.0175175823493799, 0.0472688930727053, 0.0278787334069728, 0.0236727211994869)
c(`2.5%` = -0.321412408332877, `2.5%` = -0.360033194654434, `2.5%` = -0.317756875891385, `2.5%` = -0.310112746266069, `2.5%` = -0.321047087440019, `2.5%` = -0.307177857312271, `2.5%` = -0.406584875693101, `2.5%` = -0.302290577496734, `2.5%` = -0.329787608837027, `2.5%` = -0.325741416529682, `2.5%` = -0.15743258849236, `2.5%` = -0.31119118357692, `2.5%` = -0.317021340734379, `2.5%` = -0.431037121901406, `2.5%` = -0.095511016993371, `2.5%` = 0.02041143019079, `2.5%` = -0.305991043265743, `2.5%` = -0.30655610684263,
`2.5%` = -0.319852685329391, `2.5%` = -0.276270824232982, `2.5%` = -0.304861628467873, `2.5%` = -0.311752202314792)
c(`97.5%` = 0.343837322664501, `97.5%` = 0.295622079182328, `97.5%` = 0.349107813430285, `97.5%` = 0.355203673240806, `97.5%` = 0.349024698020337, `97.5%` = 0.360808144158849, `97.5%` = 0.249517798279291, `97.5%` = 0.358750370961986, `97.5%` = 0.33508908205543, `97.5%` = 0.337658598779989, `97.5%` = 0.421101378052922, `97.5%` = 0.354555256028663, `97.5%` = 0.350403071909054, `97.5%` = 0.22676112069751, `97.5%` = 0.422731018753381, `97.5%` = 0.85608235301133, `97.5%` = 0.355759840642227, `97.5%` = 0.356934774044409,
`97.5%` = 0.341627016198812, `97.5%` = 0.376205200194986, `97.5%` = 0.358952915535868, `97.5%` = 0.352180233725197)
c(`5%` = -0.25720973558682, `5%` = -0.294903363605129, `5%` = -0.257137304097466, `5%` = -0.248399306392637, `5%` = -0.25489751531943, `5%` = -0.247102777254339, `5%` = -0.339933290032092, `5%` = -0.242533928470576, `5%` = -0.263620928816618, `5%` = -0.263152155503003, `5%` = -0.112232006084965, `5%` = -0.246916752820145, `5%` = -0.255886271822305, `5%` = -0.360056361494536, `5%` = -0.0582870053082083, `5%` = 0.0634526303087552, `5%` = -0.245278803753055, `5%` = -0.246842321323342, `5%` = -0.256280286172,
`5%` = -0.217436243551559, `5%` = -0.244210801606863, `5%` = -0.250885342909289)
c(`95%` = 0.285370104912777, `95%` = 0.243010994205006, `95%` = 0.289287710051617, `95%` = 0.297571077262736, `95%` = 0.291325959161563, `95%` = 0.299270475058976, `95%` = 0.200063580704579, `95%` = 0.298824142626635, `95%` = 0.27722780854366, `95%` = 0.278261424943046, `95%` = 0.365441233493439, `95%` = 0.297355276712413, `95%` = 0.290718931165702, `95%` = 0.178465709918192, `95%` = 0.373392398003416, `95%` = 0.753336516739962, `95%` = 0.297312097796899, `95%` = 0.297460388207995, `95%` = 0.285527407612361,
`95%` = 0.317952486884081, `95%` = 0.296773071637121, `95%` = 0.292674820916317)

@ -0,0 +1,10 @@
c("Blood & Immune system", "Circulatory", "Congential", "Contact with Healthcare", "Digestive", "Ear and Mastoid", "Endocrine, Nutritional, and Metabolic", "External Causes", "Eye and Adnexa", "Genitourinary", "Infections & Parasites", "Injury etc.", "Mental & Behavioral", "Musculoskeletal", "Neoplasms", "Nervous System", "Perinatal Period", "Pregancy, Childbirth, & Puerperium", "Respiratory", "Skin & Subcutaneaous tissue", "Special Purposes", "Symptoms, Signs etc.")
c(-0.00521081730211856, 0.0102255609545677, -0.00496344785285301, -0.00412970481483706, -0.00482782618675194, -0.0050365287595942, -0.0244992731496998, -0.00474024131164134, -0.00556304034621756, -0.00514633902980756, 0.0549642831190738, -0.00505116955549756, 0.000222710855606745, -0.0139890440514832, -0.101150807225687, 0.00328213613579688, -0.00511716442489377, -0.00389750763874108, -0.00529064338687045, 0.00342256724316399, -0.00450674475013338, -0.00565678046765618)
c(`2.5%` = -0.283907488368931, `2.5%` = -0.264718520415862, `2.5%` = -0.281159012081347, `2.5%` = -0.28202830088485, `2.5%` = -0.284419420868419, `2.5%` = -0.281327857726233, `2.5%` = -0.301921658351706, `2.5%` = -0.281271371584173, `2.5%` = -0.284249194010694, `2.5%` = -0.284012477531593, `2.5%` = -0.210012739588992, `2.5%` = -0.283029586218827, `2.5%` = -0.27410283519672, `2.5%` = -0.290631236010586, `2.5%` = -0.392051441442553, `2.5%` = -0.267503827888536, `2.5%` = -0.281737736791382, `2.5%` = -0.279312077145091,
`2.5%` = -0.282292027611709, `2.5%` = -0.271858847048387, `2.5%` = -0.282095546296768, `2.5%` = -0.283135697264375)
c(`97.5%` = 0.273419332183028, `97.5%` = 0.291348978934726, `97.5%` = 0.271017033043418, `97.5%` = 0.274111097548879, `97.5%` = 0.273436192936731, `97.5%` = 0.269026268053048, `97.5%` = 0.248170504583118, `97.5%` = 0.271591216677986, `97.5%` = 0.273523419916202, `97.5%` = 0.274995321113636, `97.5%` = 0.342573757255475, `97.5%` = 0.272937984720548, `97.5%` = 0.274132679138622, `97.5%` = 0.258354914663837, `97.5%` = 0.156606469826098, `97.5%` = 0.279853103150131, `97.5%` = 0.270902691342387, `97.5%` = 0.272104479124203,
`97.5%` = 0.273263017556272, `97.5%` = 0.279847543183877, `97.5%` = 0.272441175448396, `97.5%` = 0.274036307386916)
c(`5%` = -0.233812893025361, `5%` = -0.217746444191205, `5%` = -0.233921233193929, `5%` = -0.232257851816202, `5%` = -0.233567219181413, `5%` = -0.233477104858465, `5%` = -0.252962421653837, `5%` = -0.232486743487047, `5%` = -0.235070814746299, `5%` = -0.234533692066961, `5%` = -0.167107728841027, `5%` = -0.234659301068703, `5%` = -0.226762629571076, `5%` = -0.243190415663175, `5%` = -0.337956677281885, `5%` = -0.221951335704386, `5%` = -0.233061969747887, `5%` = -0.230188221811804, `5%` = -0.234247825650107,
`5%` = -0.223218309293191, `5%` = -0.235479873959263, `5%` = -0.234291225207645)
c(`95%` = 0.225018049213407, `95%` = 0.240749705129402, `95%` = 0.223576635602984, `95%` = 0.22490531538246, `95%` = 0.225150662214719, `95%` = 0.222530040783611, `95%` = 0.200572258529045, `95%` = 0.224085208533272, `95%` = 0.223765301903729, `95%` = 0.224205184960909, `95%` = 0.289724198406613, `95%` = 0.224221721966219, `95%` = 0.226948329518661, `95%` = 0.212010272021156, `95%` = 0.117095735429865, `95%` = 0.231832837318039, `95%` = 0.222364411332351, `95%` = 0.223927230144499, `95%` = 0.223829194578265,
`95%` = 0.231111983676153, `95%` = 0.225668354476114, `95%` = 0.223106259041378)

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@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0494676291479126, 0.0175175823493799, -0.0519713531203428, -0.141092626419518, -0.100269478864353, -0.0483011770497731, -0.0706566951944514, -0.0903067809957733, -0.0545919114607711, -0.00242272398017638, -0.00529064338687045, 0.00672386515176627)
c(`2.5%` = -0.353960823288628, `2.5%` = -0.319852685329391, `2.5%` = -0.530569224373654, `2.5%` = -0.422086178248832, `2.5%` = -0.35533612512543, `2.5%` = -0.30969751701722, `2.5%` = -0.328762771558244, `2.5%` = -0.347450401239575, `2.5%` = -0.34467924126698, `2.5%` = -0.271895651649722, `2.5%` = -0.282292027611709, `2.5%` = -0.264848607612733)
c(`97.5%` = 0.256663885447249, `97.5%` = 0.341627016198812, `97.5%` = 0.416128814653975, `97.5%` = 0.122884801270876, `97.5%` = 0.140134372918192, `97.5%` = 0.193515113672737, `97.5%` = 0.167756086960966, `97.5%` = 0.148714819749431, `97.5%` = 0.239492781782234, `97.5%` = 0.270026733830649, `97.5%` = 0.273263017556272, `97.5%` = 0.280170359985892)
c(`5%` = -0.29885389568916, `5%` = -0.256280286172, `5%` = -0.443110847973097, `5%` = -0.3719291117473, `5%` = -0.309480163754538, `5%` = -0.2632490885577, `5%` = -0.281813066410411, `5%` = -0.302200597441508, `5%` = -0.294475437187543, `5%` = -0.224288571128251, `5%` = -0.234247825650107, `5%` = -0.21829426001738)
c(`95%` = 0.201106127451977, `95%` = 0.285527407612361, `95%` = 0.335218886894626, `95%` = 0.0802166258592332, `95%` = 0.100605252625849, `95%` = 0.155768362847512, `95%` = 0.129300525656481, `95%` = 0.109558120218469, `95%` = 0.188021330440522, `95%` = 0.222159099161132, `95%` = 0.223829194578265, `95%` = 0.232756864140852)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0505967062178304, 0.01865599931714, -0.0431305204973958, -0.164813949931452, -0.115970648900297, -0.0569474070992618, -0.0803009641524095, -0.102290027233277, -0.0546326964547788, -0.00233302952373521, -0.00482782618675194, 0.00511136013511625)
c(`2.5%` = -0.355213104294602, `2.5%` = -0.321047087440019, `2.5%` = -0.521537560181517, `2.5%` = -0.440159920047502, `2.5%` = -0.373679807524352, `2.5%` = -0.324379242419328, `2.5%` = -0.338605161726642, `2.5%` = -0.358079997022996, `2.5%` = -0.347086498849369, `2.5%` = -0.27286212768348, `2.5%` = -0.284419420868419, `2.5%` = -0.267223017905891)
c(`97.5%` = 0.256220116158008, `97.5%` = 0.349024698020337, `97.5%` = 0.429980507934071, `97.5%` = 0.0934098582169743, `97.5%` = 0.122782511673881, `97.5%` = 0.187764012771118, `97.5%` = 0.163449179706992, `97.5%` = 0.135463410274458, `97.5%` = 0.23894631939739, `97.5%` = 0.271595831106391, `97.5%` = 0.273436192936731, `97.5%` = 0.274044451638933)
c(`5%` = -0.300950367218894, `5%` = -0.25489751531943, `5%` = -0.43620401741364, `5%` = -0.392282017795443, `5%` = -0.327592131875321, `5%` = -0.276552341418244, `5%` = -0.293674641980593, `5%` = -0.312900506044298, `5%` = -0.296193852536529, `5%` = -0.226336678780408, `5%` = -0.233567219181413, `5%` = -0.220927862811969)
c(`95%` = 0.202603902019158, `95%` = 0.291325959161563, `95%` = 0.346576238409847, `95%` = 0.053045778552792, `95%` = 0.0838312787329803, `95%` = 0.149008753739683, `95%` = 0.122846563348083, `95%` = 0.0964502516045677, `95%` = 0.18656668417393, `95%` = 0.222289991457749, `95%` = 0.225150662214719, `95%` = 0.228526975656424)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0931186973375372, 0.0472688930727053, -0.0813059076860515, -0.115696459653843, -0.0668043254017594, 0.0225267378773846, -0.00783924736360468, -0.0287628443176525, -0.0809466615050335, -0.00267620974013439, 0.00342256724316399, 0.0229027326955782)
c(`2.5%` = -0.398212841275992, `2.5%` = -0.276270824232982, `2.5%` = -0.560352091813988, `2.5%` = -0.369871784607321, `2.5%` = -0.303609657008891, `2.5%` = -0.217526831000879, `2.5%` = -0.243184811863137, `2.5%` = -0.259649581484174, `2.5%` = -0.37464941870207, `2.5%` = -0.274439135854432, `2.5%` = -0.271858847048387, `2.5%` = -0.243262927814473)
c(`97.5%` = 0.195728293212208, `97.5%` = 0.376205200194986, `97.5%` = 0.375467600073314, `97.5%` = 0.133967945394652, `97.5%` = 0.165983963699542, `97.5%` = 0.265350540741357, `97.5%` = 0.230601337710681, `97.5%` = 0.207050118076093, `97.5%` = 0.204585540113804, `97.5%` = 0.267892275489918, `97.5%` = 0.279847543183877, `97.5%` = 0.296090615801029)
c(`5%` = -0.341186799958823, `5%` = -0.217436243551559, `5%` = -0.472054693822914, `5%` = -0.32668730633076, `5%` = -0.26256729924706, `5%` = -0.178033167408505, `5%` = -0.204261113664472, `5%` = -0.222392523721118, `5%` = -0.322719512364534, `5%` = -0.227590395464131, `5%` = -0.223218309293191, `5%` = -0.197184265526973)
c(`95%` = 0.145913702571692, `95%` = 0.317952486884081, `95%` = 0.30207955992225, `95%` = 0.093183366481975, `95%` = 0.125927251547133, `95%` = 0.224177921805955, `95%` = 0.189346878001297, `95%` = 0.165962633366688, `95%` = 0.155090212003947, `95%` = 0.220911069519647, `95%` = 0.231111983676153, `95%` = 0.246925692056239)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.016726156695298, -0.0761301686125453, 0.173176112299651, -0.0875007238905653, -0.0663531879724985, 0.0263716192287277, -0.00242271539233981, -0.0381494869327325, -0.109295568325447, -0.00275503221432378, -0.0139890440514832, 0.0493113026890666)
c(`2.5%` = -0.310459552529128, `2.5%` = -0.431037121901406, `2.5%` = -0.223573014616573, `2.5%` = -0.340476599617661, `2.5%` = -0.305174376069712, `2.5%` = -0.214602193292334, `2.5%` = -0.238403789666391, `2.5%` = -0.273459885159963, `2.5%` = -0.407252271853641, `2.5%` = -0.272259113214428, `2.5%` = -0.290631236010586, `2.5%` = -0.209178899422793)
c(`97.5%` = 0.295751559042532, `97.5%` = 0.22676112069751, `97.5%` = 0.625146449622561, `97.5%` = 0.167253531302005, `97.5%` = 0.166163888071297, `97.5%` = 0.270408213531531, `97.5%` = 0.239032427936572, `97.5%` = 0.196051431168698, `97.5%` = 0.170699887327904, `97.5%` = 0.266631371530776, `97.5%` = 0.258354914663837, `97.5%` = 0.324504387608479)
c(`5%` = -0.260408972551825, `5%` = -0.360056361494536, `5%` = -0.165197877092618, `5%` = -0.295749142104736, `5%` = -0.263170921158664, `5%` = -0.174300938748019, `5%` = -0.199357322617647, `5%` = -0.232838007090428, `5%` = -0.352532667961251, `5%` = -0.22530608055078, `5%` = -0.243190415663175, `5%` = -0.166101667860902)
c(`95%` = 0.23786658788661, `95%` = 0.178465709918192, `95%` = 0.544725565756189, `95%` = 0.123888229912759, `95%` = 0.128681125268866, `95%` = 0.228097063420235, `95%` = 0.196129167554776, `95%` = 0.155695563618615, `95%` = 0.124477125901656, `95%` = 0.21899037055656, `95%` = 0.212010272021156, `95%` = 0.274559112084226)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0478593490739956, 0.0120682740554864, -0.0567196164994895, -0.126233602235583, -0.0888817238478321, -0.0319840844510598, -0.055198586240614, -0.0772497283445443, -0.0541521176630153, -0.00310971192809426, -0.00514633902980756, 0.00869308015726206)
c(`2.5%` = -0.348523219782961, `2.5%` = -0.325741416529682, `2.5%` = -0.537648621232678, `2.5%` = -0.408043017285209, `2.5%` = -0.343971909458341, `2.5%` = -0.293935837353889, `2.5%` = -0.316931983669652, `2.5%` = -0.333641043439836, `2.5%` = -0.343259904607912, `2.5%` = -0.270957011640022, `2.5%` = -0.284012477531593, `2.5%` = -0.263984097470059)
c(`97.5%` = 0.258199105421347, `97.5%` = 0.337658598779989, `97.5%` = 0.413237173559078, `97.5%` = 0.141325836240884, `97.5%` = 0.154268857189929, `97.5%` = 0.215841474017224, `97.5%` = 0.188621888649733, `97.5%` = 0.163079486802808, `97.5%` = 0.237777766149638, `97.5%` = 0.266687930004995, `97.5%` = 0.274995321113636, `97.5%` = 0.279840596472466)
c(`5%` = -0.297395770121559, `5%` = -0.263152155503003, `5%` = -0.450348871660559, `5%` = -0.357452526309299, `5%` = -0.298995454954135, `5%` = -0.246714915420225, `5%` = -0.268903804112122, `5%` = -0.285856831702031, `5%` = -0.2933097076324, `5%` = -0.224824888562106, `5%` = -0.234533692066961, `5%` = -0.215840640492215)
c(`95%` = 0.203709821019864, `95%` = 0.278261424943046, `95%` = 0.329135185773538, `95%` = 0.0975164848465818, `95%` = 0.11201114117772, `95%` = 0.174468036775523, `95%` = 0.148448833659993, `95%` = 0.122321755852338, `95%` = 0.188406047073467, `95%` = 0.218989193656767, `95%` = 0.224205184960909, `95%` = 0.230966741806046)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0499660268658585, 0.0197148498472504, -0.0421991751741288, -0.13476563953491, -0.0956058294147287, -0.0442534026160268, -0.0662861597218824, -0.0865335314057803, -0.0550797452225853, -0.00252250078632693, -0.00496344785285301, 0.00806097077518296)
c(`2.5%` = -0.350165746673952, `2.5%` = -0.317756875891385, `2.5%` = -0.518375863151681, `2.5%` = -0.414723657705109, `2.5%` = -0.35057979600666, `2.5%` = -0.306304745881982, `2.5%` = -0.323256686118706, `2.5%` = -0.342841852065351, `2.5%` = -0.345063660691308, `2.5%` = -0.272430725186905, `2.5%` = -0.281159012081347, `2.5%` = -0.262583809560454)
c(`97.5%` = 0.252568610015387, `97.5%` = 0.349107813430285, `97.5%` = 0.439646865645069, `97.5%` = 0.129542894513277, `97.5%` = 0.145184905982789, `97.5%` = 0.197603443786488, `97.5%` = 0.173229891076501, `97.5%` = 0.153760033992607, `97.5%` = 0.236924146027621, `97.5%` = 0.263988376114375, `97.5%` = 0.271017033043418, `97.5%` = 0.279367210952163)
c(`5%` = -0.298500654906565, `5%` = -0.257137304097466, `5%` = -0.434007392588596, `5%` = -0.363849520269935, `5%` = -0.30377336167253, `5%` = -0.259427189054046, `5%` = -0.277378887591161, `5%` = -0.29778671716257, `5%` = -0.294243091294835, `5%` = -0.225155935562034, `5%` = -0.233921233193929, `5%` = -0.215580888141684)
c(`95%` = 0.20049984396355, `95%` = 0.289287710051617, `95%` = 0.353130963560884, `95%` = 0.0859110309743907, `95%` = 0.105692185919512, `95%` = 0.15909647715405, `95%` = 0.13405804651131, `95%` = 0.114598752695363, `95%` = 0.18316007227917, `95%` = 0.218357594565282, `95%` = 0.223576635602984, `95%` = 0.232261579219567)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0486654863146441, 0.0236727211994869, -0.0348374667962509, -0.115895916505032, -0.0800513158310921, -0.023475914516512, -0.0466582461817656, -0.0684715865431922, -0.0537090394695628, -0.00206395314166231, -0.00565678046765618, 0.00840626979762671)
c(`2.5%` = -0.352062830672535, `2.5%` = -0.311752202314792, `2.5%` = -0.516492014350377, `2.5%` = -0.394971716793324, `2.5%` = -0.333434811543346, `2.5%` = -0.286384363759695, `2.5%` = -0.304309764526848, `2.5%` = -0.325218632099741, `2.5%` = -0.34255968704254, `2.5%` = -0.274505781494588, `2.5%` = -0.283135697264375, `2.5%` = -0.260710033426863)
c(`97.5%` = 0.257403541589351, `97.5%` = 0.352180233725197, `97.5%` = 0.445072841208461, `97.5%` = 0.154546638365113, `97.5%` = 0.162204869037247, `97.5%` = 0.222312513558577, `97.5%` = 0.200387773947608, `97.5%` = 0.175953830420771, `97.5%` = 0.240534823211121, `97.5%` = 0.271501986023693, `97.5%` = 0.274036307386916, `97.5%` = 0.276519814652463)
c(`5%` = -0.297336353504652, `5%` = -0.250885342909289, `5%` = -0.430050287469576, `5%` = -0.345255477437627, `5%` = -0.288017242271703, `5%` = -0.239293183426376, `5%` = -0.258607586912473, `5%` = -0.280518378138114, `5%` = -0.291661527567577, `5%` = -0.227689137616937, `5%` = -0.234291225207645, `5%` = -0.21336683632312)
c(`95%` = 0.202755710634796, `95%` = 0.292674820916317, `95%` = 0.360231402349028, `95%` = 0.109134691618903, `95%` = 0.123319005948664, `95%` = 0.182494091485978, `95%` = 0.158914432925447, `95%` = 0.135737605682531, `95%` = 0.187492448246279, `95%` = 0.223599356920508, `95%` = 0.223106259041378, `95%` = 0.230370019187908)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0816317285457012, 0.117270560237318, -0.0431781674057524, -0.322939255980837, -0.0445097363713965, 0.0831185962473774, 0.054469735486804, 0.00439061656478571, -0.111933746601916, -0.00900529540694934, 0.0549642831190738, 0.0234704825434495)
c(`2.5%` = -0.369067201876791, `2.5%` = -0.15743258849236, `2.5%` = -0.392971765289971, `2.5%` = -0.495385786097959, `2.5%` = -0.279907428049715, `2.5%` = -0.126136965980224, `2.5%` = -0.164686552393619, `2.5%` = -0.221766129169443, `2.5%` = -0.397011060181461, `2.5%` = -0.281051472827658, `2.5%` = -0.210012739588992, `2.5%` = -0.233328888684629)
c(`97.5%` = 0.196240544658593, `97.5%` = 0.421101378052922, `97.5%` = 0.304781682760948, `97.5%` = -0.159810477185182, `97.5%` = 0.194502628737617, `97.5%` = 0.305301279386911, `97.5%` = 0.287025096307068, `97.5%` = 0.239372401831851, `97.5%` = 0.156402075952097, `97.5%` = 0.260632526818398, `97.5%` = 0.342573757255475, `97.5%` = 0.282219317765516)
c(`5%` = -0.318536205133514, `5%` = -0.112232006084965, `5%` = -0.335854611911698, `5%` = -0.466181244375375, `5%` = -0.239813977632262, `5%` = -0.0931509430887361, `5%` = -0.13026348611388, `5%` = -0.18443291032113, `5%` = -0.347474604177594, `5%` = -0.232874112114568, `5%` = -0.167107728841027, `5%` = -0.190195428873606)
c(`95%` = 0.149606773044668, `95%` = 0.365441233493439, `95%` = 0.24519101313148, `95%` = -0.184792569485545, `95%` = 0.15345194844924, `95%` = 0.266763338434242, `95%` = 0.246022644974912, `95%` = 0.199837947046417, `95%` = 0.112535221760718, `95%` = 0.213804656879867, `95%` = 0.289724198406613, `95%` = 0.237452575327)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.315526037006588, 0.14948178706425, -0.745438348426778, 0.0393966359152392, -0.0457348007757995, 0.064106280747042, -0.0140917847275379, -0.0473660509007094, -0.242704066590673, -0.00295173909211749, -0.101150807225687, -0.0318651891745962)
c(`2.5%` = -0.642054194627079, `2.5%` = -0.095511016993371, `2.5%` = -1.12441685579914, `2.5%` = -0.194160502625767, `2.5%` = -0.277926578990489, `2.5%` = -0.162654732653132, `2.5%` = -0.246821463107613, `2.5%` = -0.281736932939805, `2.5%` = -0.543673509898535, `2.5%` = -0.271867873121147, `2.5%` = -0.392051441442553, `2.5%` = -0.272496159194591)
c(`97.5%` = -0.0498087194116947, `97.5%` = 0.422731018753381, `97.5%` = -0.396240166662077, `97.5%` = 0.291104489058118, `97.5%` = 0.186629528620266, `97.5%` = 0.30340806969423, `97.5%` = 0.218889942875867, `97.5%` = 0.182247266485996, `97.5%` = 0.0114150292406248, `97.5%` = 0.265171319133342, `97.5%` = 0.156606469826098, `97.5%` = 0.198395249398707)
c(`5%` = -0.580798660746861, `5%` = -0.0582870053082083, `5%` = -1.05984134753029, `5%` = -0.157477096682293, `5%` = -0.237601446017153, `5%` = -0.12601793998578, `5%` = -0.207070786292008, `5%` = -0.242358894302708, `5%` = -0.488379411138948, `5%` = -0.226179910621409, `5%` = -0.337956677281885, `5%` = -0.228981038446028)
c(`95%` = -0.0876108144400803, `95%` = 0.373392398003416, `95%` = -0.449885315105183, `95%` = 0.246925701935553, `95%` = 0.146465971010273, `95%` = 0.261260827352338, `95%` = 0.178110810416068, `95%` = 0.144856415039965, `95%` = -0.0267022930175043, `95%` = 0.218796743068272, `95%` = 0.117095735429865, `95%` = 0.161143364484194)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0505321895701756, 0.0177091826256191, -0.0374509867623648, -0.125776066126894, -0.0902292099576031, -0.036944329702934, -0.0591309519669422, -0.0793088083304893, -0.0543082831893662, -0.00287140656905416, -0.00521081730211856, 0.00652882287222823)
c(`2.5%` = -0.351333711658477, `2.5%` = -0.321412408332877, `2.5%` = -0.519252573751591, `2.5%` = -0.406597880159647, `2.5%` = -0.344254022808293, `2.5%` = -0.297343859139922, `2.5%` = -0.315544785108668, `2.5%` = -0.331413856081863, `2.5%` = -0.3460926221197, `2.5%` = -0.275944463803495, `2.5%` = -0.283907488368931, `2.5%` = -0.26412401679988)
c(`97.5%` = 0.252996678658013, `97.5%` = 0.343837322664501, `97.5%` = 0.438156824615533, `97.5%` = 0.142015362351499, `97.5%` = 0.154012266834766, `97.5%` = 0.207443984276725, `97.5%` = 0.181870296298027, `97.5%` = 0.158756949640892, `97.5%` = 0.23859370882391, `97.5%` = 0.268525663885088, `97.5%` = 0.273419332183028, `97.5%` = 0.279506924359323)
c(`5%` = -0.29803422118825, `5%` = -0.25720973558682, `5%` = -0.43284681982114, `5%` = -0.356137939234695, `5%` = -0.299115224405783, `5%` = -0.252322537371494, `5%` = -0.269748806995291, `5%` = -0.286403912298463, `5%` = -0.295316756003101, `5%` = -0.228422342352796, `5%` = -0.233812893025361, `5%` = -0.217405377189081)
c(`95%` = 0.199805705380915, `95%` = 0.285370104912777, `95%` = 0.353300713490598, `95%` = 0.0994967769999591, `95%` = 0.113509581613765, `95%` = 0.167490802315082, `95%` = 0.14240768840267, `95%` = 0.120221139002118, `95%` = 0.186170625673217, `95%` = 0.2234974899362, `95%` = 0.225018049213407, `95%` = 0.231060746721114)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0585983827703775, -0.0557624513358899, -0.147540114797909, -0.0438548071229014, -0.0394212013879011, 0.0495779683778335, -0.000453054277997355, -0.0472027857512424, -0.101183732558573, -0.00681543732790809, -0.0244992731496998, 0.0756452851959799)
c(`2.5%` = -0.356636178298712, `2.5%` = -0.406584875693101, `2.5%` = -0.605455988019874, `2.5%` = -0.295750042124458, `2.5%` = -0.273112681569153, `2.5%` = -0.186331398654033, `2.5%` = -0.236827961184312, `2.5%` = -0.283031319821082, `2.5%` = -0.402573667581036, `2.5%` = -0.277987677303119, `2.5%` = -0.301921658351706, `2.5%` = -0.182738362310984)
c(`97.5%` = 0.237496943950342, `97.5%` = 0.249517798279291, `97.5%` = 0.271710367913333, `97.5%` = 0.217593297859276, `97.5%` = 0.19504307737622, `97.5%` = 0.294769414462677, `97.5%` = 0.239952858853215, `97.5%` = 0.184326204801509, `97.5%` = 0.180340815442861, `97.5%` = 0.26497995981819, `97.5%` = 0.248170504583118, `97.5%` = 0.359198759844572)
c(`5%` = -0.304028644400323, `5%` = -0.339933290032092, `5%` = -0.520616290327113, `5%` = -0.254196188061864, `5%` = -0.232559443411886, `5%` = -0.147666860670196, `5%` = -0.197308104756834, `5%` = -0.242030280687931, `5%` = -0.347024621453625, `5%` = -0.230488468962024, `5%` = -0.252962421653837, `5%` = -0.139947007794807)
c(`95%` = 0.187816936293634, `95%` = 0.200063580704579, `95%` = 0.20347262465658, `95%` = 0.173544980297132, `95%` = 0.155038635197841, `95%` = 0.25235933990905, `95%` = 0.196860730183825, `95%` = 0.146126493852613, `95%` = 0.133329444707804, `95%` = 0.216270931014924, `95%` = 0.200572258529045, `95%` = 0.306122759153545)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0774004055701482, 0.0202098736769506, -0.148857275259831, -0.034756624929762, -0.0209198662802634, 0.0737245631655913, 0.0355843232922172, -0.0257770506361907, -0.101358093383466, -0.00444905498743218, 0.000222710855606745, 0.0410008650026277)
c(`2.5%` = -0.384222770661754, `2.5%` = -0.317021340734379, `2.5%` = -0.654106115127152, `2.5%` = -0.28447613031784, `2.5%` = -0.251665449535869, `2.5%` = -0.161795305781745, `2.5%` = -0.197888724987928, `2.5%` = -0.256373204834308, `2.5%` = -0.398857333530158, `2.5%` = -0.273927630545993, `2.5%` = -0.27410283519672, `2.5%` = -0.219982381931615)
c(`97.5%` = 0.218570279154564, `97.5%` = 0.350403071909054, `97.5%` = 0.307321465786219, `97.5%` = 0.226059193399154, `97.5%` = 0.218536405219445, `97.5%` = 0.325200306839703, `97.5%` = 0.279312654411686, `97.5%` = 0.207355980521146, `97.5%` = 0.182559370226462, `97.5%` = 0.264287404395679, `97.5%` = 0.274132679138622, `97.5%` = 0.3146382824935)
c(`5%` = -0.328832973524529, `5%` = -0.255886271822305, `5%` = -0.55799947646926, `5%` = -0.243764242401936, `5%` = -0.214018963569841, `5%` = -0.12427108412664, `5%` = -0.159713441998239, `5%` = -0.217062488812283, `5%` = -0.344628024841975, `5%` = -0.227858560023144, `5%` = -0.226762629571076, `5%` = -0.175242262948575)
c(`95%` = 0.168803960348435, `95%` = 0.290718931165702, `95%` = 0.231568717349548, `95%` = 0.181638021717836, `95%` = 0.175300930108115, `95%` = 0.280768005851167, `95%` = 0.236582791839493, `95%` = 0.16844496482049, `95%` = 0.132004530075709, `95%` = 0.220133939553423, `95%` = 0.226948329518661, `95%` = 0.264306220644107)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0578472700681722, 0.363548114620147, 0.514928808041493, -0.179789393683086, -0.0908978444606774, 0.0485959237871361, -0.00145174053575294, -0.0416302406262986, -0.0324576251191776, -0.00517241124667845, 0.00328213613579688, -0.0230137010884716)
c(`2.5%` = -0.359167198818045, `2.5%` = 0.02041143019079, `2.5%` = 0.0216592886163218, `2.5%` = -0.430812731714158, `2.5%` = -0.333639714164675, `2.5%` = -0.181367177838171, `2.5%` = -0.231956837333007, `2.5%` = -0.27766810096831, `2.5%` = -0.315411836398564, `2.5%` = -0.275526164264352, `2.5%` = -0.267503827888536, `2.5%` = -0.293189864865698)
c(`97.5%` = 0.238629751570793, `97.5%` = 0.85608235301133, `97.5%` = 1.17318649525454, `97.5%` = 0.0570528188192439, `97.5%` = 0.140764053180901, `97.5%` = 0.287579065151981, `97.5%` = 0.231839325930911, `97.5%` = 0.196383580001578, `97.5%` = 0.259944925352525, `97.5%` = 0.267696135908434, `97.5%` = 0.279853103150131, `97.5%` = 0.238015436387141)
c(`5%` = -0.303098555574414, `5%` = 0.0634526303087552, `5%` = 0.0851401986791414, `5%` = -0.386505748941182, `5%` = -0.290084333457996, `5%` = -0.143728029163889, `5%` = -0.193940136889492, `5%` = -0.237273417600727, `5%` = -0.266550224886603, `5%` = -0.228284369418676, `5%` = -0.221951335704386, `5%` = -0.246615923137647)
c(`95%` = 0.186931912303368, `95%` = 0.753336516739962, `95%` = 1.03873143227049, `95%` = 0.0190438837776769, `95%` = 0.102564973004199, `95%` = 0.243855515697918, `95%` = 0.193187180905901, `95%` = 0.155692997386599, `95%` = 0.205343484029368, `95%` = 0.220217569663176, `95%` = 0.231832837318039, `95%` = 0.195044859439803)

@ -0,0 +1,6 @@
c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0507912436647474, 0.0105781672515, -0.0572148794918185, -0.161324485000642, -0.11718865552377, -0.0580549952623519, -0.0821974616540054, -0.105025588883719, -0.055296341966815, -0.00219896995482389, -0.00556304034621756, 0.00596509106734287)
c(`2.5%` = -0.356770047469594, `2.5%` = -0.329787608837027, `2.5%` = -0.529409792355877, `2.5%` = -0.44209572260938, `2.5%` = -0.373553837099913, `2.5%` = -0.325433458075037, `2.5%` = -0.344635367302557, `2.5%` = -0.361334615741075, `2.5%` = -0.348019495991554, `2.5%` = -0.272173859797933, `2.5%` = -0.284249194010694, `2.5%` = -0.264838971088612)
c(`97.5%` = 0.255694095814266, `97.5%` = 0.33508908205543, `97.5%` = 0.408657439741233, `97.5%` = 0.101657962161228, `97.5%` = 0.11864634098921, `97.5%` = 0.186079165001043, `97.5%` = 0.157815589258783, `97.5%` = 0.131395254082946, `97.5%` = 0.235175513197134, `97.5%` = 0.268729163024419, `97.5%` = 0.273523419916202, `97.5%` = 0.274146522142649)
c(`5%` = -0.301053900765771, `5%` = -0.263620928816618, `5%` = -0.445215274649135, `5%` = -0.391137998579351, `5%` = -0.328258365252273, `5%` = -0.276463334286846, `5%` = -0.297022738992198, `5%` = -0.315922917337871, `5%` = -0.297136938616546, `5%` = -0.224813386072165, `5%` = -0.235070814746299, `5%` = -0.216692707544591)
c(`95%` = 0.200369696005793, `95%` = 0.27722780854366, `95%` = 0.328590570058774, `95%` = 0.0578686050827066, `95%` = 0.0817009261712685, `95%` = 0.147963763976249, `95%` = 0.119977584917821, `95%` = 0.0949818456263718, `95%` = 0.186846293810823, `95%` = 0.221009192368411, `95%` = 0.223765301903729, `95%` = 0.226800701259279)

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c("Elapsed Duration", "asinh(Competitors USPDC)", "asinh(Generic Brands)", "asinh(High SDI)", "asinh(High-Medium SDI)", "asinh(Low SDI)", "asinh(Low-Medium SDI)", "asinh(Medium SDI)", "status_ANR", "status_EBI", "status_NYR", "status_Rec")
c(-0.0561236542390722, -0.0174830982131017, -0.114801759701441, -0.0489532404314588, -0.00995833322809683, 0.0764993233097176, 0.0602798840227049, 0.0304789175922322, -0.0491179148659016, -0.0020229135961933, 0.0102255609545677, -0.0121276026193075)
c(`2.5%` = -0.358192918691032, `2.5%` = -0.360033194654434, `2.5%` = -0.588446720987112, `2.5%` = -0.297868077807792, `2.5%` = -0.240899712415657, `2.5%` = -0.162465078674946, `2.5%` = -0.17414438609744, `2.5%` = -0.201017363333911, `2.5%` = -0.340513734259116, `2.5%` = -0.272921161056328, `2.5%` = -0.264718520415862, `2.5%` = -0.284982548735974)
c(`97.5%` = 0.245199739323497, `97.5%` = 0.295622079182328, `97.5%` = 0.326892147498506, `97.5%` = 0.210710410280741, `97.5%` = 0.229119750480018, `97.5%` = 0.332077723102122, `97.5%` = 0.312602029054938, `97.5%` = 0.277230334088767, `97.5%` = 0.247596369898235, `97.5%` = 0.269687555821123, `97.5%` = 0.291348978934726, `97.5%` = 0.25166727687992)
c(`5%` = -0.304624731177692, `5%` = -0.294903363605129, `5%` = -0.498779889626974, `5%` = -0.256277233535303, `5%` = -0.202637633223219, `5%` = -0.125070759586198, `5%` = -0.13517180498734, `5%` = -0.163740873087956, `5%` = -0.29096401042673, `5%` = -0.225192615705392, `5%` = -0.217746444191205, `5%` = -0.235700053008877)
c(`95%` = 0.193775727317953, `95%` = 0.243010994205006, `95%` = 0.251902327224973, `95%` = 0.165019140778464, `95%` = 0.188705917246998, `95%` = 0.287176225295342, `95%` = 0.267926957380469, `95%` = 0.233147083774771, `95%` = 0.194446427538144, `95%` = 0.222074828728455, `95%` = 0.240749705129402, `95%` = 0.206639994505824)

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% latex table generated in R 4.4.2 by xtable 1.8-4 package
% Sun Feb 2 01:37:17 2025
\begin{table}[ht]
\centering
\begin{tabular}{r}
\hline
Value \\
\hline
-0.226 \\
-0.013 \\
-0.005 \\
-0.001 \\
-0.000 \\
0.000 \\
0.000 \\
0.002 \\
0.005 \\
0.008 \\
0.011 \\
0.014 \\
0.018 \\
0.022 \\
0.027 \\
0.032 \\
0.039 \\
0.047 \\
0.057 \\
0.073 \\
0.272 \\
\hline
\end{tabular}
\end{table}

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