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42 lines
2.0 KiB
Plaintext
42 lines
2.0 KiB
Plaintext
\begin{tikzpicture}
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\begin{pgfonlayer}{nodelayer}
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\node [style=Red Box] (0) at (4, -1.5) {Will Terminate?};
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\node [style=Red Box] (1) at (-4.25, -1.5) {Market Measures};
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\node [style=emptyBox] (4) at (-6, -7.5) {Unobserved};
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\node [style=Red Box] (5) at (-0.25, 2) {Enrollment Status};
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\node [style=Red Box] (8) at (-5.75, -6) {Relationships of interest};
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\node [style=emptyBox] (9) at (12.25, 6.25) {Fundamental Efficacy/Safety};
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\node [style=emptyBox] (10) at (-0.25, 8) {Previously Observed Efficacy/Safety};
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\node [style=emptyBox] (12) at (14, 0.25) {Currently Observed Efficacy/Safety};
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\node [style=Gray Box] (13) at (7, -6) {Observed};
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\node [style=Gray Box] (18) at (-6.5, 1.5) {Population};
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\node [style=Gray Box] (20) at (-0.25, 5) {Decision to procced with Phase III};
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\node [style=Gray Box] (21) at (0, -3.5) {Condition};
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\node [style=Gray Box] (22) at (7.25, 2.75) {Elapsed Duration};
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\end{pgfonlayer}
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\begin{pgfonlayer}{edgelayer}
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\draw [style=RightArrow] (18) to (5);
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\draw [style=RightArrow] (18) to (1);
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\draw [style=RightArrow] (9) to (10);
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\draw [style=RightArrow] (10) to (20);
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\draw [style=RightArrow] (9) to (12);
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\draw [style=RightArrow] (12) to (0);
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\draw [style=Light Arrow] (21) to (1);
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\draw [style=Light Arrow] (21) to (0);
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\draw [style=Light Arrow, in=-120, out=165, looseness=2.00] (21) to (18);
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\draw [style=Light Arrow, in=180, out=180, looseness=2.75] (21) to (20);
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\draw [style=Light Arrow, bend right=60, looseness=1.75] (21) to (9);
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\draw [style=Light Arrow] (21) to (5);
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\draw [style=RightArrow, in=-180, out=165, looseness=2.00] (1) to (20);
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\draw [style=RightArrow] (20) to (5);
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\draw [style=RightArrow] (22) to (0);
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\draw [style=RightArrow, bend left] (20) to (0);
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\draw [style=PurpleArrow] (1) to (0);
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\draw [style=PurpleArrow] (1) to (5);
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\draw [style=PurpleArrow] (5) to (0);
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\draw [style=PurpleArrow, in=135, out=45, loop] (8) to ();
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\draw [style=lightredarrow] (22) to (5);
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\draw [style=lightredarrow] (5) to (22);
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\end{pgfonlayer}
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\end{tikzpicture}
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