From 87ab7a6b1d1759ed9cb170c3282463f158da3a20 Mon Sep 17 00:00:00 2001 From: Will King Date: Wed, 9 Feb 2022 10:10:23 -0800 Subject: [PATCH] Update 'Concept paper 2022 02 09' --- Concept-paper-2022-02-09.md | 14 +++++++++++--- 1 file changed, 11 insertions(+), 3 deletions(-) diff --git a/Concept-paper-2022-02-09.md b/Concept-paper-2022-02-09.md index 3686e49..b8f78ed 100644 --- a/Concept-paper-2022-02-09.md +++ b/Concept-paper-2022-02-09.md @@ -32,14 +32,22 @@ This would use the IND or similar data to build the list of phase transitions. ### Design tradeoffs Some design tradeoffs include -- Normalized or non-normalized transition paths? I'm particularly interested in inclucing mixed-phase paths. +- Normalized or non-normalized transition paths? I'm particularly interested in inclucing mixed-phase paths, i.e. non-normalized paths. ## Overall Model -Overall this would allow me to construct a probabalistic description of passing through the d +Overall this would allow me to construct a probabalistic description of passing through the trials portion of the R&D pipeline. +The probabalistic model could then be used to answer various questions, including causal/structural questions. +It would also be straightforward to develop simulations from this approach, as the probabilities are right there. # Estimation Strategy -Probably use a non-parametric bayesian approach to estimating the probability densities. +Probably use a non-parametric bayesian approach to estimating the probability densities? ## Identification Strategy +### Descriptive identification + + +### Causal Identification +Not of interest right now. +