You cannot select more than 25 topics
Topics must start with a letter or number, can include dashes ('-') and can be up to 35 characters long.
144 lines
12 KiB
Plaintext
144 lines
12 KiB
Plaintext
<mxfile host="Electron" agent="Mozilla/5.0 (X11; Linux x86_64) AppleWebKit/537.36 (KHTML, like Gecko) draw.io/26.0.9 Chrome/128.0.6613.186 Electron/32.2.5 Safari/537.36" version="26.0.9">
|
|
<diagram name="Page-1" id="mtO3n3LGiMWHk561vA-H">
|
|
<mxGraphModel dx="1434" dy="796" grid="1" gridSize="10" guides="1" tooltips="1" connect="1" arrows="1" fold="1" page="1" pageScale="1" pageWidth="3300" pageHeight="2339" math="0" shadow="0">
|
|
<root>
|
|
<mxCell id="0" />
|
|
<mxCell id="1" parent="0" />
|
|
<mxCell id="rB942MAWg83VmefqhkrR-1" value="Enrollment Level" style="swimlane;fontStyle=0;childLayout=stackLayout;horizontal=1;startSize=30;horizontalStack=0;resizeParent=1;resizeParentMax=0;resizeLast=0;collapsible=1;marginBottom=0;whiteSpace=wrap;html=1;fillColor=#d5e8d4;strokeColor=#0000FF;perimeterSpacing=1;strokeWidth=4;fillStyle=zigzag-line;" parent="1" vertex="1">
|
|
<mxGeometry x="560" y="430" width="120" height="60" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-2" value="Enrollment Status" style="text;strokeColor=#0000FF;fillColor=#ffe6cc;align=left;verticalAlign=middle;spacingLeft=4;spacingRight=4;overflow=hidden;points=[[0,0.5],[1,0.5]];portConstraint=eastwest;rotatable=0;whiteSpace=wrap;html=1;strokeWidth=4;perimeterSpacing=1;" parent="rB942MAWg83VmefqhkrR-1" vertex="1">
|
|
<mxGeometry y="30" width="120" height="30" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-5" value="Will it Terminate?" style="rounded=0;whiteSpace=wrap;html=1;fillColor=#f8cecc;strokeColor=#0000FF;strokeWidth=4;fillStyle=dots;" parent="1" vertex="1">
|
|
<mxGeometry x="840" y="520" width="120" height="60" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-6" value="Enrollment Process<br>Parameters" style="rounded=0;whiteSpace=wrap;html=1;fillColor=#d5e8d4;strokeColor=#82b366;fillStyle=zigzag-line;" parent="1" vertex="1">
|
|
<mxGeometry x="560" y="241" width="120" height="60" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-27" style="edgeStyle=orthogonalEdgeStyle;rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0.5;entryY=0;entryDx=0;entryDy=0;strokeWidth=3;" parent="1" source="rB942MAWg83VmefqhkrR-7" target="rB942MAWg83VmefqhkrR-5" edge="1">
|
|
<mxGeometry relative="1" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-7" value="Elapsed Duration" style="rounded=0;whiteSpace=wrap;html=1;fillColor=#ffe6cc;strokeColor=#d79b00;" parent="1" vertex="1">
|
|
<mxGeometry x="840" y="360" width="120" height="60" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-9" value="Population" style="rounded=0;whiteSpace=wrap;html=1;fillColor=#ffe6cc;strokeColor=#d79b00;" parent="1" vertex="1">
|
|
<mxGeometry x="440" y="460" width="60" height="60" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-10" value="Market Conditions" style="rounded=0;whiteSpace=wrap;html=1;fillColor=#ffe6cc;strokeColor=#d79b00;" parent="1" vertex="1">
|
|
<mxGeometry x="500" y="520" width="60" height="60" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-12" value="Is likely Safe and Effective" style="swimlane;fontStyle=0;childLayout=stackLayout;horizontal=1;startSize=30;horizontalStack=0;resizeParent=1;resizeParentMax=0;resizeLast=0;collapsible=1;marginBottom=0;whiteSpace=wrap;html=1;fillColor=#d5e8d4;strokeColor=#82b366;fillStyle=zigzag-line;" parent="1" vertex="1">
|
|
<mxGeometry x="770" y="242" width="120" height="59" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-13" value="Decision to proceed with Phase III trial" style="text;strokeColor=#d79b00;fillColor=#ffe6cc;align=left;verticalAlign=middle;spacingLeft=4;spacingRight=4;overflow=hidden;points=[[0,0.5],[1,0.5]];portConstraint=eastwest;rotatable=0;whiteSpace=wrap;html=1;" parent="rB942MAWg83VmefqhkrR-12" vertex="1">
|
|
<mxGeometry y="30" width="120" height="29" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-29" style="edgeStyle=orthogonalEdgeStyle;rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0.5;entryY=0;entryDx=0;entryDy=0;strokeWidth=3;exitX=0.5;exitY=1;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-6" target="rB942MAWg83VmefqhkrR-1" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="619.5" y="320" as="sourcePoint" />
|
|
<mxPoint x="619.5" y="380" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-30" style="rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=1;entryY=0.5;entryDx=0;entryDy=0;strokeWidth=3;exitX=0;exitY=0.25;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-12" target="rB942MAWg83VmefqhkrR-6" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="610" y="151" as="sourcePoint" />
|
|
<mxPoint x="610" y="211" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-31" style="rounded=0;orthogonalLoop=1;jettySize=auto;html=1;strokeWidth=3;entryX=1;entryY=0.25;entryDx=0;entryDy=0;exitX=0;exitY=0.5;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-34" target="rB942MAWg83VmefqhkrR-12" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="980" y="221" as="sourcePoint" />
|
|
<mxPoint x="720" y="101" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-33" value="Current Trial Safety and Efficacy" style="rounded=0;whiteSpace=wrap;html=1;fillColor=#d5e8d4;strokeColor=#82b366;fillStyle=zigzag-line;" parent="1" vertex="1">
|
|
<mxGeometry x="1001" y="520" width="115" height="60" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-34" value="Previously Observed Safety and Efficacy" style="rounded=0;whiteSpace=wrap;html=1;fillColor=#d5e8d4;strokeColor=#82b366;fillStyle=zigzag-line;" parent="1" vertex="1">
|
|
<mxGeometry x="1001" y="241" width="115" height="60" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-35" value="Fundamental Safety and Efficacy" style="rounded=0;whiteSpace=wrap;html=1;fillColor=#d5e8d4;strokeColor=#82b366;fillStyle=zigzag-line;" parent="1" vertex="1">
|
|
<mxGeometry x="1001" y="390" width="115" height="60" as="geometry" />
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-39" style="rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=1;entryY=0.5;entryDx=0;entryDy=0;strokeWidth=3;exitX=0;exitY=0.5;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-33" target="rB942MAWg83VmefqhkrR-5" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="1090" y="530" as="sourcePoint" />
|
|
<mxPoint x="1090" y="590" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-45" style="edgeStyle=orthogonalEdgeStyle;rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0.5;entryY=1;entryDx=0;entryDy=0;strokeWidth=3;exitX=0.5;exitY=0;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-35" target="rB942MAWg83VmefqhkrR-34" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="961" y="330" as="sourcePoint" />
|
|
<mxPoint x="961" y="390" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-46" style="edgeStyle=orthogonalEdgeStyle;rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0.5;entryY=0;entryDx=0;entryDy=0;strokeWidth=3;exitX=0.5;exitY=1;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-35" target="rB942MAWg83VmefqhkrR-33" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="971" y="340" as="sourcePoint" />
|
|
<mxPoint x="971" y="400" as="targetPoint" />
|
|
<Array as="points">
|
|
<mxPoint x="1061" y="490" />
|
|
<mxPoint x="1061" y="490" />
|
|
</Array>
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-48" style="edgeStyle=orthogonalEdgeStyle;rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0;entryY=0.5;entryDx=0;entryDy=0;strokeWidth=3;exitX=0.5;exitY=0;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-9" target="rB942MAWg83VmefqhkrR-6" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="400" y="380" as="sourcePoint" />
|
|
<mxPoint x="400" y="440" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-51" style="rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0;entryY=0.5;entryDx=0;entryDy=0;strokeWidth=3;exitX=1;exitY=0.5;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-10" target="rB942MAWg83VmefqhkrR-5" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="670" y="600" as="sourcePoint" />
|
|
<mxPoint x="670" y="660" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-52" style="edgeStyle=orthogonalEdgeStyle;rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0.75;entryY=1;entryDx=0;entryDy=0;strokeWidth=3;exitX=0;exitY=0.5;exitDx=0;exitDy=0;strokeColor=#1A1A1A;" parent="1" source="rB942MAWg83VmefqhkrR-10" target="rB942MAWg83VmefqhkrR-9" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="430" y="515" as="sourcePoint" />
|
|
<mxPoint x="430" y="575" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-54" style="edgeStyle=orthogonalEdgeStyle;rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0.25;entryY=0;entryDx=0;entryDy=0;strokeWidth=3;exitX=1;exitY=0.5;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-9" target="rB942MAWg83VmefqhkrR-10" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="569.5" y="435" as="sourcePoint" />
|
|
<mxPoint x="569.5" y="495" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-60" style="edgeStyle=orthogonalEdgeStyle;rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0;entryY=0.75;entryDx=0;entryDy=0;strokeWidth=3;exitX=0.5;exitY=0;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-10" target="rB942MAWg83VmefqhkrR-6" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="480" y="530" as="sourcePoint" />
|
|
<mxPoint x="570" y="280" as="targetPoint" />
|
|
<Array as="points">
|
|
<mxPoint x="530" y="285" />
|
|
</Array>
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-59" style="rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0;entryY=0.25;entryDx=0;entryDy=0;strokeWidth=4;exitX=1;exitY=0.5;exitDx=0;exitDy=0;jumpStyle=arc;jumpSize=14;strokeColor=#0000FF;" parent="1" source="rB942MAWg83VmefqhkrR-2" target="rB942MAWg83VmefqhkrR-5" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="740" y="480" as="sourcePoint" />
|
|
<mxPoint x="740" y="540" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-64" style="edgeStyle=orthogonalEdgeStyle;rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0.75;entryY=0;entryDx=0;entryDy=0;strokeWidth=3;exitX=0;exitY=0.25;exitDx=0;exitDy=0;" parent="1" source="rB942MAWg83VmefqhkrR-7" target="rB942MAWg83VmefqhkrR-1" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="650" y="380" as="sourcePoint" />
|
|
<mxPoint x="650" y="440" as="targetPoint" />
|
|
<Array as="points">
|
|
<mxPoint x="650" y="375" />
|
|
</Array>
|
|
</mxGeometry>
|
|
</mxCell>
|
|
<mxCell id="rB942MAWg83VmefqhkrR-66" style="edgeStyle=orthogonalEdgeStyle;rounded=0;orthogonalLoop=1;jettySize=auto;html=1;entryX=0.25;entryY=1;entryDx=0;entryDy=0;strokeWidth=3;exitX=1;exitY=0.25;exitDx=0;exitDy=0;strokeColor=#999999;" parent="1" source="rB942MAWg83VmefqhkrR-1" target="rB942MAWg83VmefqhkrR-7" edge="1">
|
|
<mxGeometry relative="1" as="geometry">
|
|
<mxPoint x="650" y="380" as="sourcePoint" />
|
|
<mxPoint x="650" y="440" as="targetPoint" />
|
|
</mxGeometry>
|
|
</mxCell>
|
|
</root>
|
|
</mxGraphModel>
|
|
</diagram>
|
|
</mxfile>
|