\documentclass[../Main.tex]{subfiles} \graphicspath{{\subfix{Assets/img/}}} \begin{document} Identifying commercial impediments to successfully completing clinical trials in otherwise capable pharmaceuticals will hopefully lead to a more robust and competitive pharmaceutical market. %FIXTAG: too much "hopefully" Although the current state of this research is insufficient to draw robust conclusions, these early results suggest that delaying the close of enrollment period reduces the probability of termination of a trial. %FIXTAG: OK for now but I think there might be a better way to handle this for now % The successful completion of Phase III clinical trials is crucial for % bringing new treatments to market. %FIXTAG: needs to be earlier The primary limitation that must be addressed before drawing a strong conclusion is that of insufficient data. %FIXTAG: This needs rewritten This takes two forms. %FIXTAG: needs better transition The first is the small sample size. To overcome this requires an improved data matching approach and a revised data scraper. %FIXTAG: active voice: this can be overcome by... The second is creating a model of enrollment that can be used to address the causal identification issue from the joint determination of enrollment statuses and elapsed durations of trials. %FIXTAG: sentence is too complicated Despite these limitations, this work establishes a framework for analyzing operational versus strategic factors in clinical trial completion. %FIXTAG: analyzing replaced with "separating causal effects" The approach developed here can be extended with additional data to provide more definitive guidance on enrollment management strategies. %FIXTAG: the approach here + additional data can provide %FIXTAG: tie to next sentence better Further research in this direction could help reduce operational barriers to trial completion or estimating the impact policies may have through operational channels.%FIXTAG: clauses don't match. first clause needs tightened. Ultimately this work will hopefully support more efficient drug development and increased market competition. %FIXTAG: wishy-washy and duplicative. \end{document}