diff --git a/Paper/sections/02_data.tex b/Paper/sections/02_data.tex index 8d8eabc..0f8fb62 100644 --- a/Paper/sections/02_data.tex +++ b/Paper/sections/02_data.tex @@ -131,11 +131,13 @@ drug compound may be packaged in multiple ways, e.g. boxes with different numbers of blister packs. These SPLs are made available for download so that they can be integrated into patient health systems to improve patient safety -\cite{indexingsplfactsheet_}. +\cite{usfda_splfactsheet_2023}. The FDA also published additional data in the NDC SPL Data Elements (NSDE) file. This file contains some of the data from the SPL files, as well as the dates when each product was approved for sale and when it was removed from the market. +This summary of SPLs is what I used to find which drugs were approved +to be on the market at a given date. %Structured Product Labels and dates of marketing % Key features @@ -186,7 +188,7 @@ In each section below I briefly describe each terminology, its contents, and use The Medical Subject Headings (MeSH) Thesaurus is produced and maintained by the National Library of Medicine. It is used to index subjects in various NLM publications including PubMed -\cite{medicalsubjectheadingshomepage_}. +\cite{usnlm_meshhomepage_2023}. The AACT database contains a table that links clinical trials' clinical conditions and drug names to terms in the MeSH thesaurus. As this contains a standardized nomenclature, it simplified much of the @@ -216,7 +218,7 @@ The one I chose to use was a MariaDB database that backs a service called RxNav provided by the National Library of Medicine (NLM). The NLM provides scripts to set up and host the backing databases on your own servers -\cite{usnlm_rxnaviabox_2023}. +\cite{usnlm_rxnavinabox_2023}. After setting up the local server, I wrote a python program to export the data from the RxNorm database and import it into the AACT Database. This was required because the former uses a MariaDB database server diff --git a/assets/preambles/References.bib b/assets/preambles/References.bib index 6357e51..7ed2641 100644 --- a/assets/preambles/References.bib +++ b/assets/preambles/References.bib @@ -637,11 +637,6 @@ file = {/home/will/Zotero/storage/23DGMZ5X/en.html} } -@misc{indexingsplfactsheet_, - title = {Indexing {{Spl Fact Sheet}}}, - file = {/home/will/Zotero/storage/KAHW2ABD/Indexing-SPL-Fact-Sheet.pdf} -} - @misc{interviewadamgeorge_2023, title = {Interview with {{Adam George}}.}, date = {2023-05-05} @@ -812,16 +807,6 @@ isbn = {978-0-367-13991-9} } -@online{medicalsubjectheadingshomepage_, - type = {Product, Program, and Project Descriptions}, - title = {Medical {{Subject Headings}} - {{Home Page}}}, - publisher = {U.S. National Library of Medicine}, - url = {https://www.nlm.nih.gov/mesh/meshhome.html}, - urldate = {2023-04-09}, - langid = {english}, - file = {/home/will/Zotero/storage/RTW5EPBG/meshhome.html} -} - @online{officepublicaffairsjusticedepartment_2020, title = {Office of {{Public Affairs}} | {{Justice Department Announces Global Resolution}} of {{Criminal}} and {{Civil Investigations}} with {{Opioid Manufacturer Purdue Pharma}} and {{Civil Settlement}} with {{Members}} of the {{Sackler Family}} | {{United States Department}} of {{Justice}}}, date = {2020-10-21T10:05:07-04:00}, @@ -1045,6 +1030,15 @@ file = {/home/will/Zotero/storage/7ADA2YND/2022 ICD-10-PCS Official Guidelines for Coding and Reporting.pdf} } +@misc{usfda_splfactsheet_2023, + title = {Indexing {{Spl Fact Sheet}}}, + author = {{U.S. Food and Drug Administration}}, + url = {https://www.fda.gov/media/85645/download}, + urldate = {2023-04-08}, + organization = {U.S. Food and Drug Administration}, + file = {/home/will/Zotero/storage/KAHW2ABD/Indexing-SPL-Fact-Sheet.pdf} +} + @online{usnlm_fdaaa800finalrule, type = {Government}, title = {{{FDAAA}} 801 and the {{Final Rule}} - {{ClinicalTrials}}.Gov}, @@ -1056,7 +1050,18 @@ file = {/home/will/Zotero/storage/V9YVGVK2/fdaaa.html} } -@online{usnlm_rxnavinabos_2023, +@online{usnlm_meshhomepage_2023, + type = {Product, Program, and Project Descriptions}, + title = {Medical {{Subject Headings}} - {{Home Page}}}, + author = {{U.S. National Library of Medicine}}, + publisher = {U.S. National Library of Medicine}, + url = {https://www.nlm.nih.gov/mesh/meshhome.html}, + urldate = {2023-04-09}, + langid = {english}, + file = {/home/will/Zotero/storage/RTW5EPBG/meshhome.html} +} + +@online{usnlm_rxnavinabox_2023, title = {{{RxNav-in-a-Box}} - {{RxNav Applications}}}, author = {{U.S. National Library of Medicine}}, url = {https://lhncbc.nlm.nih.gov/RxNav/applications/RxNav-in-a-Box.html},