diff --git a/Latex/Paper/sections/01_introduction.tex b/Latex/Paper/sections/01_introduction.tex
index 9f1a113..291a55b 100644
--- a/Latex/Paper/sections/01_introduction.tex
+++ b/Latex/Paper/sections/01_introduction.tex
@@ -20,4 +20,17 @@ competitors already in the market or close to entering and the overall demand to
 While discovering that a drug doesn't work or is unsafe is a scientific failure, other failure modes occur.
 \cite{khmelnitskaya_competitionattritiondrug_2021} explored how to identify business related failures within the drug development pipeline. 
 
+Thoughts so far
+types of failure: 
+- scientific: unsafe or ineffective
+- business: concerns about profitability
+- operational: cannot actually complete the steps required to bring things to market.
+
+Things that influence each
+- scientific: phamokynetics, biology. Take as given.
+- business: regulation, competitors, demand levels, patents, etc
+- operational: regulation, finding participants, finding competent PIs etc.
+
+Maybe financial and operational terminology?
+
 \end{document}